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[糖尿病患者的便秘]

[Constipation in patients with diabetes mellitus].

作者信息

Rossol Siegbert

机构信息

Medizinische Klinik, Krankenhaus Nordwest, Frankfurt am Main.

出版信息

MMW Fortschr Med. 2007 Nov 1;149(44):39-42. doi: 10.1007/BF03365174.

Abstract

Up to 60% of the patients with diabetes mellitus suffer from gastrointestinal tract symptoms that arise pathogenetically from a disturbance of the autonomous nervous system. Patient age, disease duration and poor control of diabetes mellitus correlate positively with the presence of gastrointestinal symptoms. Chronic constipation, in addition to diarrhoea, gall bladder dysfunction and incontinence, is increasingly regarded as a serious problem and for the first time, is now considered in the current guidelines of the professional societies. Modern diagnosis and treatment facilitate systematic control of the symptoms. Treatment necessitates long-term intake of laxatives, proper diabetes control and other accompanying general measures such as adequate amounts of liquids, dietary fibre and exercise. Motility and secretion-stimulating, osmotically active or locally applied laxatives are used. Slow transit constipation, which is typically observed in diabetics, can be best controlled with polyethylene glycol, bisacodyl or sodium picosulphate.

摘要

高达60%的糖尿病患者患有胃肠道症状,这些症状在发病机制上源于自主神经系统紊乱。患者年龄、病程以及糖尿病控制不佳与胃肠道症状的出现呈正相关。除腹泻、胆囊功能障碍和大小便失禁外,慢性便秘日益被视为一个严重问题,并且首次在专业协会的现行指南中得到考虑。现代诊断和治疗有助于系统控制这些症状。治疗需要长期服用泻药、适当控制糖尿病以及采取其他伴随的一般措施,如摄入足够的液体、膳食纤维和进行运动。使用促进动力和分泌、具有渗透活性或局部应用的泻药。糖尿病患者中典型出现的慢传输型便秘,使用聚乙二醇、比沙可啶或匹可硫酸钠能得到最佳控制。

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