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白癜风相关瘢痕处的复发性结节病。

Recurrent sarcoidosis on a scar associated with vitiligo.

作者信息

Demirkök Sevtap Sipahi, Arzuhal Nurcan, Devranoğlu Gevher, Demirkesen Cuyan, Tüzün Yalçin

机构信息

Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey.

出版信息

J Dermatol. 2007 Dec;34(12):829-33. doi: 10.1111/j.1346-8138.2007.00394.x.

Abstract

We report a case of systemic sarcoidosis, diagnosed 13 years ago by transbronchial biopsy. Our patient had a spontaneous resolution of hilar and mediastinal lymphadenopathy 6 months after diagnosis. She presented with a skin rash on her thyroidectomy scar after a period of 4 years of complete remission. The patient complained that her thyroidectomy incision scar rose up, reddened and hardened. Biopsy of the skin lesion revealed non-caseating epithelioid granulomas with histiocytes and multinucleated giant cells. She was successfully treated with oral prednisone. Scar sarcoidosis recurred twice in a 7-year follow-up period without accompanying systemic sarcoidosis. Vitiligo appeared with the last relapse of scar sarcoidosis. The case we present is of interest due to the recurrent attacks of scar sarcoidosis in a patient during the remission period of systemic sarcoidosis. Another aspect of this case is the association of the disease with vitiligo without any sign of an autoimmune disease.

摘要

我们报告一例系统性结节病,13年前经支气管活检确诊。我们的患者在诊断后6个月时,肺门和纵隔淋巴结病自行消退。在完全缓解4年后,她的甲状腺切除术后瘢痕处出现皮疹。患者主诉其甲状腺切除切口瘢痕隆起、发红且变硬。皮肤病变活检显示有非干酪样上皮样肉芽肿,伴有组织细胞和多核巨细胞。她接受口服泼尼松治疗后痊愈。在7年的随访期内,瘢痕结节病复发两次,未伴有系统性结节病。白癜风在瘢痕结节病最后一次复发时出现。我们呈现的该病例很有意思,因为在系统性结节病缓解期患者的瘢痕结节病出现了反复发作。该病例的另一个方面是疾病与白癜风相关,且无任何自身免疫性疾病迹象。

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