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鸡蛋过敏

Egg allergy.

作者信息

Kemp Andrew S

机构信息

Department of Allergy and Immunology, The Children's Hospital at Westmead, Sydney, Australia.

出版信息

Pediatr Allergy Immunol. 2007 Dec;18(8):696-702. doi: 10.1111/j.1399-3038.2007.00679.x.

DOI:10.1111/j.1399-3038.2007.00679.x
PMID:18078424
Abstract

Egg allergy is one of the most common food allergies in infants and young children. The great majority is not life-threatening and management involves exclusion of egg from the diet and regular review with the expectation that the majority of children will outgrow the allergy by school age. Judgment is required as to when the dietary elimination of egg is no longer required. This decision may be helped by demonstrating loss of sensitivity by skin prick or specific IgE testing and in some cases a supervised food challenge. Particular issues in management arise with more severe, potentially life-threatening reactions, with immunization with vaccines prepared in eggs, with the diagnosis of egg hypersensitivity as a cause of delayed exacerbations of eczema which can be non-IgE mediated, and in deciding whether a child can be allowed to ingest small amounts of cooked egg through egg-containing foods while continuing to avoid raw egg or larger amounts of whole egg. Cases which illustrate these issues are presented.

摘要

鸡蛋过敏是婴幼儿最常见的食物过敏之一。绝大多数情况并不危及生命,管理措施包括从饮食中排除鸡蛋,并定期复查,因为大多数儿童到学龄期会不再对鸡蛋过敏。需要判断何时不再需要从饮食中排除鸡蛋。通过皮肤点刺试验或特异性IgE检测显示敏感性消失,以及在某些情况下进行有监督的食物激发试验,可能有助于做出这一决定。在管理方面,对于更严重、可能危及生命的反应、用鸡蛋制备的疫苗进行免疫接种、将鸡蛋超敏反应诊断为湿疹延迟加重的原因(这可能是非IgE介导的)以及决定儿童在继续避免生鸡蛋或大量全蛋的同时是否可以通过含鸡蛋的食物摄入少量熟鸡蛋等问题,会出现一些特殊情况。文中展示了说明这些问题的病例。

相似文献

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Egg allergy.鸡蛋过敏
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[Feature of food allergy developed during infancy (1)--relationship between infantile atopic dermatitis and food allergy].婴儿期发生的食物过敏特征(1)——婴儿特应性皮炎与食物过敏的关系
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Does food allergy cause atopic dermatitis? Food challenge testing to dissociate eczematous from immediate reactions.食物过敏会导致特应性皮炎吗?食物激发试验以区分湿疹样反应和速发型反应。
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Skin prick test to egg white provides additional diagnostic utility to serum egg white-specific IgE antibody concentration in children.对儿童进行蛋清皮肤点刺试验,相对于血清中蛋清特异性IgE抗体浓度而言,能提供额外的诊断效用。
J Allergy Clin Immunol. 2006 Apr;117(4):842-7. doi: 10.1016/j.jaci.2005.12.1304. Epub 2006 Mar 3.

引用本文的文献

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The influence of the time and temperature of heat treatment on the allergenicity of egg white proteins.热处理的时间和温度对蛋清蛋白变应原性的影响。
Allergy Asthma Immunol Res. 2013 Mar;5(2):96-101. doi: 10.4168/aair.2013.5.2.96. Epub 2012 Nov 2.
2
The study of egg allergy in children with atopic dermatitis.儿童特应性皮炎的鸡蛋过敏研究。
World Allergy Organ J. 2009 Jul;2(7):123-7. doi: 10.1097/WOX.0b013e3181abe7cb.
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Regulatory B cells and allergic diseases.调节性 B 细胞与过敏性疾病。
Allergy Asthma Immunol Res. 2011 Jul;3(3):168-77. doi: 10.4168/aair.2011.3.3.168. Epub 2011 May 30.