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对于回肠原位膀胱替代术和回肠导管的输尿管回肠吻合术,围手术期是否放置支架?一项前瞻性随机试验的结果。

To stent or not to stent perioperatively the ureteroileal anastomosis of ileal orthotopic bladder substitutes and ileal conduits? Results of a prospective randomized trial.

作者信息

Mattei Agostino, Birkhaeuser Frederic D, Baermann Christian, Warncke Sebastian H, Studer Urs E

机构信息

Department of Urology, University Hospital of Bern, Bern, Switzerland.

出版信息

J Urol. 2008 Feb;179(2):582-6. doi: 10.1016/j.juro.2007.09.066. Epub 2007 Dec 21.

DOI:10.1016/j.juro.2007.09.066
PMID:18078958
Abstract

PURPOSE

We evaluated the impact of stenting the ureteroileal anastomosis on its competence, upper urinary tract dilatation, gastrointestinal recovery, metabolic parameters and patency rate after cystectomy with ileal bladder substitution or ileal conduit.

MATERIALS AND METHODS

A total of 54 patients (37 with an ileal bladder substitute and 17 with an ileal conduit) were prospectively randomized into 2 groups, with (29) or without (25) perioperative stenting of the ureteroileal anastomosis. In all cases an end-to-side ureteroileal refluxing anastomosis was performed. The stents were removed after 5 to 10 days. The parameters assessed postoperative days 1, 3 and 7 were creatinine concentration from the wound drains, upper urinary tract dilatation, time to bowel function recovery, serum creatinine, as well as urea and incidence of metabolic acidosis.

RESULTS

Median patient age was 68 years (range 45 to 85). Urine leak on postoperative day 1 was more frequent in those anastomoses without stents, and on postoperative days 3 and 7 the values were comparable. Stenting of the ureteroileal anastomosis resulted in significantly decreased early postoperative upper urinary tract dilatation, improved recovery of bowel function and decreased metabolic acidosis. In either group no patient had clinical evidence of ureteroileal anastomotic stricture during the early postoperative period. Three patients with perioperative stenting required surgical or endoscopic treatment for a stricture of the ureteroileal anastomosis during the 12-month followup.

CONCLUSIONS

Stenting of the ureteroileal anastomosis allows for significantly less frequent incidence of early postoperative dilatation of the pelvicaliceal system, bowel activity resumes significantly earlier and metabolic acidosis is significantly less frequent.

摘要

目的

我们评估了输尿管回肠吻合口支架置入对其功能、上尿路扩张、胃肠道恢复、代谢参数以及膀胱切除术后回肠膀胱替代术或回肠导管的通畅率的影响。

材料与方法

总共54例患者(37例行回肠膀胱替代术,17例行回肠导管术)被前瞻性随机分为两组,一组(29例)在输尿管回肠吻合口进行围手术期支架置入,另一组(25例)未置入。所有病例均行端侧输尿管回肠抗反流吻合术。支架在5至10天后取出。评估术后第1、3和7天的参数包括伤口引流液中的肌酐浓度、上尿路扩张情况、肠功能恢复时间、血清肌酐、尿素以及代谢性酸中毒的发生率。

结果

患者中位年龄为68岁(范围45至85岁)。术后第1天,未置入支架的吻合口漏尿更为常见,而术后第3天和第7天,两组数值相当。输尿管回肠吻合口支架置入导致术后早期上尿路扩张明显减轻、肠功能恢复改善以及代谢性酸中毒减少。在术后早期,两组均无患者有输尿管回肠吻合口狭窄的临床证据。在12个月的随访期间,3例围手术期置入支架的患者因输尿管回肠吻合口狭窄需要手术或内镜治疗。

结论

输尿管回肠吻合口支架置入可使肾盂肾盏系统术后早期扩张的发生率显著降低,肠道活动恢复明显提前,代谢性酸中毒的发生率显著降低。

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