Koek H L, de Bruin A, Gast A, Gevers E, Kardaun J W P F, Reitsma J B, Grobbee D E, Bots M L
Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, the Netherlands.
Neth J Med. 2007 Dec;65(11):434-41.
To study the incidence of first acute myocardial infarction (AMi) in the Netherlands.
We recently showed that AMi patients can be followed longitudinally within dutch national medical registrations in a valid way. This makes it possible to provide nationwide incidence estimates of first AMi in the Netherlands.
New cases of first AMi in the dutch population in 2000 were identified through linkage of the national hospital discharge register, the population register and the cause of death statistics and included hospitalised first Ami patients and out-of-hospital deaths from first AMi.
31,777 patients with a first AMi were identified. The incidence (per 100,000 persons per year) increased from 2 in men aged <30 years to 2996 in men aged > or = 90 years. Corresponding figures for women ranged from 1 to 2226. The incidence was higher in men than in women in all age groups, but the male-to-female ratio decreased after the age of 50-59 year. Of all first AMI patients, 40% died before being admitted to a hospital. The proportion of non-hospitalised AMI patients increased with age in men after the age of 50-59 years. Within the age groups the proportion of out-of-hospital deaths was similar for men and women.
Our study provides the first nationwide incidence estimates of first AMI in the Netherlands. Expected differences in incidence with regard to age and gender were shown. The large proportion of out-of-hospital deaths reinforces the importance of primary prevention AMI.
研究荷兰首次急性心肌梗死（AMI）的发病率。
我们最近表明，在荷兰国家医疗登记系统中，可以有效地对AMI患者进行纵向随访。这使得提供荷兰首次AMI的全国发病率估计成为可能。
通过将国家医院出院登记册、人口登记册和死亡原因统计数据相链接，确定了2000年荷兰人群中首次AMI的新病例，其中包括首次AMI住院患者和首次AMI导致的院外死亡病例。
共识别出31777例首次AMI患者。发病率（每年每10万人）从年龄小于30岁男性的2例增加到年龄大于或等于90岁男性的2996例。女性的相应数字为1至2226例。在所有年龄组中，男性的发病率均高于女性，但在50 - 59岁之后，男女比例下降。在所有首次AMI患者中，40%在入院前死亡。50 - 59岁之后，男性中未住院的AMI患者比例随年龄增加。在各年龄组中，男性和女性的院外死亡比例相似。
我们的研究提供了荷兰首次AMI的首个全国发病率估计。显示了年龄和性别方面预期的发病率差异。院外死亡比例高强化了AMI一级预防的重要性。
