McGill D J, Hutchison C, McKenzie E, McSherry E, Mackay I R
Laser Suite, Canniesburn Plastic Surgery Unit, Jubilee Building, Glasgow Royal Infirmary, 84 Castle Street, Glasgow, UK.
Lasers Surg Med. 2007 Dec;39(10):767-72. doi: 10.1002/lsm.20584.
Despite the high incidence of polycystic ovary syndrome (PCOS) in women attending for facial hair removal there are few studies looking specifically at this patient group. We carried out a split-face study directly comparing the efficacy of a 3 milliseconds pulse duration alexandrite laser with the Lumina IPL system in 38 women with PCOS.
Each patient underwent six treatments using both systems, with 1, 3 and 6 months follow-up. Hair counts, hair-free intervals and patient satisfaction were recorded for all patients.
After six treatments, alexandrite laser treatment resulted in longer median hair-free intervals when compared to IPL (7 weeks vs. 2 weeks; P < 0.001). Decrease in hair counts was significantly larger on the Alexandrite side compared to the IPL side at 1, 3 and 6 months (52%, 43% and 46% vs. 21%, 21% and 27%; P < 0.001). Patient satisfaction scores, using linear analogue scales (LAS), at 1, 3 and 6 months were significantly higher for the alexandrite laser than the IPL (8.7, 7.8 and 7.7 vs. 5.7, 5.1 and 5.1; P < or = 0.002).
The alexandrite laser resulted in significantly longer hair-free intervals, a larger reduction in hair counts and greater patient satisfaction than the IPL and appeared to be more effective in this patient group. It is clear from the results in this study that the GentleLase alexandrite laser is more effective at reducing facial hirsutism in women with PCOS than the Lumina IPL. It is probable that this is due to the specific wavelength, short pulse duration and single pulse delivery of the GentleLase alexandrite laser, resulting in more follicular destruction than the IPL.
尽管在因面部脱毛前来就诊的女性中，多囊卵巢综合征（PCOS）的发病率很高，但专门针对该患者群体的研究却很少。我们进行了一项半脸研究，直接比较了3毫秒脉宽的翠绿宝石激光与Lumina强脉冲光（IPL）系统对38例PCOS女性的疗效。
每位患者使用这两种系统各接受6次治疗，并进行1、3和6个月的随访。记录所有患者的毛发计数、毛发无生长间隔时间和患者满意度。
经过6次治疗后，与IPL相比，翠绿宝石激光治疗后的毛发无生长间隔时间中位数更长（7周对2周；P < 0.001）。在1、3和6个月时，翠绿宝石激光治疗侧的毛发计数减少量明显大于IPL治疗侧（分别为52%、43%和46%对21%、21%和27%；P < 0.001）。在1、3和6个月时，使用线性模拟量表（LAS）评估的患者满意度得分，翠绿宝石激光显著高于IPL（分别为8.7、7.8和7.7对5.7、5.1和5.1；P ≤ 0.002）。
与IPL相比，翠绿宝石激光导致的毛发无生长间隔时间显著更长，毛发计数减少幅度更大，患者满意度更高，且在该患者群体中似乎更有效。从本研究结果可以明显看出，GentleLase翠绿宝石激光在减少PCOS女性面部多毛方面比Lumina IPL更有效。这可能是由于GentleLase翠绿宝石激光特定的波长、短脉宽和单脉冲发射，导致比IPL对毛囊的破坏更多。
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