Al-Dhalimi Muhsin A, Kadhum Mohammad J
a Department of Dermatology , College of Medicine, University of Kufa , Najaf , Iraq.
J Cosmet Laser Ther. 2015;17(5):267-72. doi: 10.3109/14764172.2015.1027223.
Undesirable hair growth presents a significant problem for many patients. Photoepilation has become a very popular procedure in esthetic and cosmetic practice. Among the systems used are the long-pulsed alexandrite laser (755 nm) (ALX) and intense pulsed light (IPL).
To compare the safety and efficacy of long-pulsed ALX and IPL for hair removal.
This comparative study was carried out in the outpatient Department of Dermatology and Venereology, Al-Sadir Teaching Hospital, Al Najaf City during the period from June 2009 to July 2010. Thirty-five patients were included; thirty of them completed the study. They received six treatment sessions with the ALX on the left side of the face and IPL on the right side of face with 4-week intervals between sessions. Response to treatment on both sides of the face was assessed at 1, 3, and 6 treatment sessions. Hair-free intervals and patient's satisfaction were recorded in each visit.
After six treatment sessions, IPL-treated sides showed longer median hair-free intervals compared with ALX-treated sides. Reduction in hair counts was significantly larger on the IPL compared with that on the ALX-treated sides at 1, 3, and 6 sessions. Three patients (10%) developed postinflammatory hyperpigmentation, one of them on the left side and the others on the right side. It was more severe on the right side and both the patients were of skin type IV. Slight stinging and burning sensation at time of the treatment were recorded in all patients. All reported side effects were transient and tolerated by the patients except postinflammatory hyperpigmentation which persisted and was decreasing gradually toward the end of the study.
The results of this study suggested that IPL is more effective in reducing excessive facial hair growth, with longer hair-free intervals and greater patient satisfaction than the ALX.
毛发过度生长给许多患者带来了重大问题。光脱毛术在美容和整形实践中已成为一种非常流行的治疗方法。所使用的系统包括长脉冲翠绿宝石激光（755纳米）（ALX）和强脉冲光（IPL）。
比较长脉冲ALX和IPL用于脱毛的安全性和有效性。
这项比较研究于2009年6月至2010年7月在纳杰夫市萨迪尔教学医院皮肤科和性病科门诊进行。纳入35例患者；其中30例完成了研究。他们在面部左侧接受6次ALX治疗，在面部右侧接受IPL治疗，每次治疗间隔4周。在第1、3和6次治疗时评估面部两侧的治疗反应。每次就诊时记录毛发无生长间隔时间和患者满意度。
经过6次治疗后，与接受ALX治疗一侧相比，接受IPL治疗一侧的毛发无生长间隔时间中位数更长。在第1、3和6次治疗时，与接受ALX治疗一侧相比，IPL治疗一侧的毛发数量减少更为显著。3例患者（10%）出现炎症后色素沉着，其中1例在左侧，另外2例在右侧。右侧更为严重，这2例患者均为IV型皮肤。所有患者在治疗时均记录有轻微刺痛和烧灼感。除炎症后色素沉着持续存在且在研究接近结束时逐渐减轻外，所有报告的副作用均为短暂性且患者可耐受。
本研究结果表明，IPL在减少面部过多毛发方面更有效，与ALX相比，其毛发无生长间隔时间更长，患者满意度更高。
