Pinkhardt E H, Sperfeld A-D, Bretschneider V, Unrath A, Ludolph A C, Kassubek J
Department of Neurology, University of Ulm, Ulm, Germany.
Acta Neurol Scand. 2008 Jun;117(6):409-14. doi: 10.1111/j.1600-0404.2007.00964.x. Epub 2007 Dec 12.
Magnetic resonance imaging (MRI) is considered the most sensitive modality for evaluating spinal epidural lipomatosis (SEL) in vivo. The aim of this study was to compare the existing MRI classifications of SEL and to reevaluate the clinico-radiological correlation of SEL as a pathological entity.
Measurements of the cervical, thoracic and lumbar spine were performed in a retrospective setting within 1406 data sets from the digital MRI archives.
It could be shown that the existing MRI classifications developed for different spinal regions complemented each other. However, there was no distinct correlation of these MRI findings with clinical symptoms because other morphological changes existed that probably caused the patients' complaints.
Existing SEL classifications developed either for the lumbar or the thoracic spine were found to be applicable to both regions, but the very vague association with clinical symptoms should caution against premature conclusions with respect to the clinical significance of SEL.
磁共振成像(MRI)被认为是在体内评估脊髓硬膜外脂肪增多症(SEL)最敏感的方式。本研究的目的是比较现有的SEL的MRI分类,并重新评估SEL作为一种病理实体的临床-放射学相关性。
在回顾性研究中,对来自数字MRI档案的1406个数据集中的颈椎、胸椎和腰椎进行测量。
可以看出,针对不同脊柱区域制定的现有MRI分类相互补充。然而,这些MRI表现与临床症状之间没有明显的相关性,因为存在其他可能导致患者不适的形态学变化。
发现现有的针对腰椎或胸椎制定的SEL分类适用于两个区域,但与临床症状的非常模糊的关联应提醒不要对SEL的临床意义过早下结论。