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超声引导下肋下前入路肝活检与传统Menghini技术的随机试验。

A randomized trial of ultrasound-guided anterior subcostal liver biopsy versus the conventional Menghini technique.

作者信息

Papini E, Pacella C M, Rossi Z, Bizzarri G, Fabbrini R, Nardi F, Picardi R

机构信息

Department of Internal Medicine, Ospedale Regina Apostolorum, Albano Laziale, Rome, Italy.

出版信息

J Hepatol. 1991 Nov;13(3):291-7. doi: 10.1016/0168-8278(91)90071-i.

DOI:10.1016/0168-8278(91)90071-i
PMID:1808221
Abstract

An ultrasound-guided double pass biopsy technique using a large bore cutting needle via an anterior subcostal route (USAB) is described. The diagnostic adequacy of this biopsy procedure was evaluated in comparison with the traditional Menghini technique in 200 cases of suspected chronic liver disease randomly assigned to the two different procedures. Retrieval rate was better in the USAB group. The sample length was less than 15 mm in four cases in the USAB group and in 19 cases in the Menghini group. In three cases in the USAB group the second pass modified the diagnosis of the first specimen from chronic active hepatitis to active cirrhosis. In order to evaluate the safety and discomfort of the two procedures 340 patients assigned to the different techniques had liver ultrasound scans 6 and 24 h following percutaneous biopsy. USAB was associated with a reduced frequency of complications (one out of 170 patients vs. seven out of 170 patients who had the intercostal Menghini procedure). In our study, USAB seems to offer better sampling and size of individual samples, together with reduced frequency of major and minor complications.

摘要

描述了一种使用大口径切割针经肋下前路的超声引导双针穿刺活检技术(USAB)。在200例疑似慢性肝病患者中,将其随机分为两组,分别采用该活检方法和传统的Menghini技术,比较两种方法的诊断充分性。USAB组的取材成功率更高。USAB组有4例样本长度小于15 mm,Menghini组有19例。USAB组有3例,第二次穿刺将第一次标本的诊断从慢性活动性肝炎修正为活动性肝硬化。为了评估两种方法的安全性和不适感,340例接受不同技术的患者在经皮活检后6小时和24小时进行肝脏超声检查。USAB的并发症发生率较低(170例患者中有1例发生并发症,而接受肋间Menghini技术的170例患者中有7例发生并发症)。在我们的研究中,USAB似乎能提供更好的取材和单个样本的大小,同时减少了严重和轻微并发症的发生率。

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