Glaser J, Mann O, von Eiff M, Pfahlberg A, Pausch J
Abteilung für Allgemeine Innere Medizin und Gastroenterologie, Herz-Jesu-Krankenhaus Fulda.
Med Klin (Munich). 1995 Mar 1;90(3):131-3.
Recently, a high incidence of ultrasound-detected hepatic hematomas due to percutaneous liver biopsy has been reported. Until yet, little is known about the incidence of asymptomatic hepatic hematomas following sonographically guided fine-needle biopsy.
For that reason, we carried out a prospective study with sonographic examinations before and after liver biopsy in 160 patients. 51 patients, aged 50 to 83, median 67 years, with focal liver lesions had ultrasound-guided liver biopsy using the 0.95 mm-cut biopsy-needle, in 109 patients (17 to 80, median 49 years) with diffuse liver disease percutaneous liver biopsy with the 1.4 mm-needle of Menghini was performed.
After fine-needle biopsy none of the 51 patients with focal liver lesions displayed liver hematoma on ultrasonography. In the group of patients who underwent percutaneous Menghini biopsy a liver hematoma, sized up to 12 x 5 cm in diameter, occurred four times (3.7%).
The results of this study indicate that fine-needle biopsy of the liver is a particularly safe diagnostic procedure, when compared with percutaneous Menghini biopsy.
最近，有报道称经皮肝穿刺活检后超声检测到的肝血肿发生率很高。迄今为止，关于超声引导下细针穿刺活检后无症状肝血肿的发生率知之甚少。
因此，我们对160例患者进行了一项肝活检前后超声检查的前瞻性研究。51例年龄在50至83岁（中位年龄67岁）的局灶性肝病变患者采用0.95毫米切割活检针进行超声引导下肝活检，109例（年龄17至80岁，中位年龄49岁）弥漫性肝病患者采用门基尼1.4毫米针进行经皮肝穿刺活检。
51例局灶性肝病变患者在细针穿刺活检后超声检查均未显示肝血肿。在接受经皮门基尼活检的患者组中，出现了4次肝血肿（3.7%），直径最大达12×5厘米。
本研究结果表明，与经皮门基尼活检相比，肝细针穿刺活检是一种特别安全的诊断方法。
