Mossakowska Malgorzata, Barcikowska Maria, Broczek Katarzyna, Grodzicki Tomasz, Klich-Raczka Alicja, Kupisz-Urbanska Malgorzata, Podsiadly-Marczykowska Teresa, Sikora Ewa, Szybinska Aleksandra, Wieczorowska-Tobis Katarzyna, Zyczkowska Jolanta, Kuznicki Jacek
International Institute of Molecular and Cell Biology, Warsaw, Poland.
Exp Gerontol. 2008 Mar;43(3):238-44. doi: 10.1016/j.exger.2007.10.014. Epub 2007 Nov 6.
Studies of centenarians as a model of successful ageing may help identify various environmental, social, psychological, and genetic factors supporting longevity. The scientific aims of the programme were to assess health status and environmental determinants of ageing of Polish centenarians, and to collect biological material for studying selected aspects of longevity, including genetic factors. The social aim of the project was to bring public attention to ageing of the population, as well as living conditions of elderly individuals. The intention of the authors of this paper is to present aims, scope, methods and preliminary results of the Polish Centenarians Programme, as well as to provide potential new partners for studying various aspects of longevity and ageing with the information about available materials collected during the programme. In this study, 346 subjects aged 100+ were visited, biological material was collected from 285 subjects, and 153 lymphocyte cell lines were immortalized.
将百岁老人作为成功老龄化的模型进行研究，可能有助于识别支持长寿的各种环境、社会、心理和遗传因素。该项目的科学目标是评估波兰百岁老人的健康状况和衰老的环境决定因素，并收集生物材料以研究长寿的选定方面，包括遗传因素。该项目的社会目标是引起公众对人口老龄化以及老年人生活条件的关注。本文作者的目的是介绍波兰百岁老人项目的目标、范围、方法和初步结果，并通过提供该项目期间收集的可用材料信息，为研究长寿和老龄化各个方面提供潜在的新合作伙伴。在这项研究中，走访了346名100岁及以上的受试者，从285名受试者身上收集了生物材料，并建立了153个永生淋巴细胞系。
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