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[1例因胸部X线异常阴影诊断为无症状副神经节瘤的病例]

[A case of asymptomatic paraganglioma diagnosed by abnormal shadow on chest X-ray].

作者信息

Fujiuchi S, Fujita Y, Ohki Y, Fujikane T, Sasaki N, Shimizu T, Sakai E, Kubo Y, Onodera S

机构信息

First Department of Internal Medicine, Asahikawa Medical College, Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Dec;29(12):1618-23.

PMID:1808387
Abstract

A 65-year-old man was noted to have an abnormal shadow on chest X-ray at mass screening examination, and was seen at Douhoku Byoin National Sanatorium. Chest X-ray showed a homogeneous mass shadow and a lytic lesion of the right 5th rib with extra-pleural tumor sign at the right upper and middle lung fields. Retroperitoneal tumor of 5 cm in diameter was detected in the right adrenal area by ultrasonography. Because of increasing plasma levels of norepinephrine and dopamine, the diagnosis of malignant pheochromocytoma with rib metastasis was made. Histologically, chromogranin staining was positive in each resected specimen. The retroperitoneal tumor was separate from the right adrenal gland. We report a rare case of malignant paraganglioma which was asymptomatic in spite of increasing plasma levels of catecholamines.

摘要

一名65岁男性在大规模筛查检查时胸部X线显示有异常阴影,遂前往Douhoku Byoin国立疗养院就诊。胸部X线显示右上和中肺野有均匀的肿块阴影以及右侧第5肋骨的溶骨性病变,伴有胸膜外肿瘤征。超声检查在右肾上腺区域发现直径5 cm的腹膜后肿瘤。由于去甲肾上腺素和多巴胺血浆水平升高,诊断为伴有肋骨转移的恶性嗜铬细胞瘤。组织学上,每个切除标本的嗜铬粒蛋白染色均为阳性。腹膜后肿瘤与右肾上腺分离。我们报告一例罕见的恶性副神经节瘤病例,尽管儿茶酚胺血浆水平升高,但患者无症状。

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