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[一例巨大腹膜后副神经节瘤]

[A case of giant retroperitoneal paraganglioma].

作者信息

Osaka Kimito, Yokonishi Tetsuhiro, Ito Yusuke, Komiya Atsushi, Kobayashi Kazuki, Sakai Naoki, Noguchi Sumio, Kishi Hiroichi, Tsuura Yukio

机构信息

The Department of Urology, Yokosuka Kyosai Hospital, Japan.

出版信息

Hinyokika Kiyo. 2010 Jul;56(7):377-80.

Abstract

Paraganglioma is a rare neuroendocrine tumor which arises from extra adrenal paraganglionic cells of the autonomic nervous system. We report a case of a giant retroperitoneal paraganglioma. A 43-year-old man referred to our hospital for further examination of a retroperitoneal mass. The patient had neither familial nor past medical history. The blood and urine test, laboratory examinations including cathecolamines, were unremarkable. Abdominal computed tomography showed an enhancing solid mass 13 cm in diameter on the left kidney. The invasion to the left kidney was suspected. Angiography showed the left renal, splenic, middle suprarenal and left inferior diaphragmatic artery feeding the tumor. The splenic and left inferior diaphragmatic artery were embolized before surgical treatment. The tumor, left kidney, adrenal gland and spleen were surgically resected. Histological examination revealed extra-adrenal paraganglioma, and there was no invasion of the tumor to the left kidney, adrenal gland and spleen. The patient has now survived more than 10 months following the surgery without tumor recurrence.

摘要

副神经节瘤是一种罕见的神经内分泌肿瘤,起源于自主神经系统的肾上腺外副神经节细胞。我们报告一例巨大腹膜后副神经节瘤病例。一名43岁男性因腹膜后肿块前来我院进一步检查。该患者既无家族病史也无既往病史。血液和尿液检查,包括儿茶酚胺的实验室检查均无异常。腹部计算机断层扫描显示左肾有一个直径13厘米的强化实性肿块。怀疑肿瘤侵犯左肾。血管造影显示左肾动脉、脾动脉、肾上腺中动脉和左膈下动脉为肿瘤供血。在手术治疗前对脾动脉和左膈下动脉进行了栓塞。手术切除了肿瘤、左肾、肾上腺和脾脏。组织学检查显示为肾上腺外副神经节瘤,肿瘤未侵犯左肾、肾上腺和脾脏。该患者术后已存活超过10个月,无肿瘤复发。

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