Jurkiewicz J, Czernicki Z, Pawłowski G, Matysiak E
Kliniki Neurochirurgii CMDiK PAN, Warszawie.
Neurol Neurochir Pol. 1991 Sep-Oct;25(5):567-73.
The experiment was carried out on 19 cats with changed intracranial volume-pressure relations by means of an epidural balloon which was inflated to 1.0 ml volume over 60 minutes. The intracranial pressure, the resistance to cerebrospinal fluid resorption, the volume-pressure responses and visual evoked potentials were determined at balloon volumes of 0.3 ml, 0.5 ml, 0.8 ml, 1.0 ml, 1.3 ml, 1.5 ml, 1.8 ml, 2.0 ml and 2.3 ml. It was demonstrated that intracranial pressure is of important informative value only after exhaustion of 63% of the intracranial volume reserve. This value of the volume-pressure responses and resistance to CSF resorption appeared after exhaustion of 28% of this reserve, and the visual evoked potentials were changed after exhaustion of 43% of the reserve. The correlation coefficient between these parameters was high during decompensation. At the time of compensation of the volume the correlation coefficient between the intracranial pressure and the remaining determined parameters was only 0.6.
该实验在19只通过硬膜外球囊改变颅内容积 - 压力关系的猫身上进行，球囊在60分钟内充气至1.0毫升容积。在球囊容积为0.3毫升、0.5毫升、0.8毫升、1.0毫升、1.3毫升、1.5毫升、1.8毫升、2.0毫升和2.3毫升时，测定颅内压、脑脊液吸收阻力、容积 - 压力反应和视觉诱发电位。结果表明，只有在颅内容积储备耗尽63%后，颅内压才具有重要的信息价值。容积 - 压力反应和脑脊液吸收阻力的值在该储备耗尽28%后出现，视觉诱发电位在储备耗尽43%后发生变化。在失代偿期间，这些参数之间的相关系数很高。在容积代偿时，颅内压与其余测定参数之间的相关系数仅为0.6。
