嗜麦芽窄食单胞菌L1和L2β-内酰胺酶的诱导
Induction of L1 and L2 beta-lactamases of Stenotrophomonas maltophilia.
作者信息
Hu Rouh-Mei, Huang Kuang-Jay, Wu Lii-Tzu, Hsiao Ying-Ju, Yang Tsuey-Ching
机构信息
Department of Biotechnology and Bioinformatics, Asia University, Taichung 413, Taiwan.
出版信息
Antimicrob Agents Chemother. 2008 Mar;52(3):1198-200. doi: 10.1128/AAC.00682-07. Epub 2007 Dec 17.
Abstract
Isogenic L1 and L2 gene knockout mutants of Stenotrophomonas maltophilia KJ (KJDeltaL1 and KJDeltaL2, respectively) were constructed by xylE gene replacement. Induction kinetics of the L1 and L2 genes were evaluated by testing catechol 2,3-dioxygenase activity in the mutants. The results suggested that the induction of the L1 and L2 genes was differentially regulated.
摘要
通过木糖操纵子基因替换构建了嗜麦芽窄食单胞菌KJ的等基因L1和L2基因敲除突变体（分别为KJDeltaL1和KJDeltaL2）。通过检测突变体中儿茶酚2,3-双加氧酶活性来评估L1和L2基因的诱导动力学。结果表明，L1和L2基因的诱导受到差异调节。
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