Al-Hwiesh Abdulla K
King Fahd University Hospital, Al Khobar, Saudi Arabia.
Saudi J Kidney Dis Transpl. 2008 Jan;19(1):82-6.
Calciphylaxis is a dreaded complication of chronic renal failure characterized by nodular subcutaneous calcification and pain. Full tissue necrosis often leads to ulceration, secondary infection and high mortality rate. We herewith present a 65-year-old Saudi gentleman who presented with multiple necrotic skin lesions of both proximal and distal distribution. Skin biopsy confirmed the diagnosis of calciphylaxis. Patient was started on sevelamer hydrochloride and low calcium dialysate to which he responded dramatically without the need for parathyroidectomy. To our knowledge, this is the first reported case of calciphylaxis with both proximal and distal distribution.
钙过敏是慢性肾衰竭一种可怕的并发症，其特征为皮下结节状钙化和疼痛。全层组织坏死常导致溃疡、继发感染及高死亡率。我们在此报告一位65岁的沙特男性，他出现了近端和远端分布的多处坏死性皮肤病变。皮肤活检确诊为钙过敏。患者开始服用盐酸司维拉姆并使用低钙透析液，对此他反应显著，无需进行甲状旁腺切除术。据我们所知，这是首例近端和远端均有分布的钙过敏病例报告。
