Horner K C, Rydmarker S
Laboratoire d'Audiologie Expérimentale, Inserm U 229, Université Bordeaux II, Hôpital Pellegrin, France.
Scanning Microsc. 1991 Sep;5(3):755-65.
Morpho-pathological features, observed by scanning electron microscopy, in guinea pigs with endolymphatic hydrops of 4-14 months included shortening of the hair cell tufts, loss of tufts, retraction of sensory hair cells away from the surrounding tissue and hair cell loss. After 22 months of hydrops, there was complete loss of hair cells with indifferentiation of the epithelium. The loss of ciliary tufts involved loss of both stereocilia and kinocilia identified as short stubs and holes respectively. Control macular epithelia showed no hair tuft loss although ampullae in control ears could show some loss.
通过扫描电子显微镜观察，4至14个月内淋巴积水豚鼠的形态病理学特征包括毛细胞纤毛束缩短、纤毛束缺失、感觉毛细胞从周围组织退缩以及毛细胞丢失。积水22个月后，毛细胞完全丢失，上皮细胞出现去分化。纤毛束的丢失涉及静纤毛和动纤毛的丢失，分别表现为短残端和空洞。对照黄斑上皮未见毛束丢失，尽管对照耳的壶腹可能有一些丢失。
