牛血清和尿液中胃复安的测定。
Determination of metoclopramide in the serum and urine of cattle.
作者信息
Jones R D, Bowen J M
机构信息
Department of Veterinary Physiology and Pharmacology, University of Georgia, Athens 30602.
出版信息
Vet Hum Toxicol. 1991 Dec;33(6):551-3.
PMID:1808828
Abstract
Metoclopramide, a dopamine-2 agent, has been shown to be useful in the antagonism of fescue toxicosis in grazing steers. The determination of this drug is described for the purpose of pharmacokinetic study and consideration of potential delivery devices to combat this economically significant condition.
摘要
甲氧氯普胺是一种多巴胺-2受体拮抗剂，已被证明可有效对抗放牧公牛的牛茅草中毒。为了进行药代动力学研究以及考虑对抗这种具有重大经济影响疾病的潜在给药装置，本文描述了该药物的测定方法。
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