自身免疫性疾病与女性患者。

Autoimmune disease and the female patient.

作者信息

Schreiber Andrea

机构信息

Department of Oral and Maxillofacial Surgery, New York University College of Dentistry, 345 East 24th Street, New York, NY 10010, USA.

出版信息

Oral Maxillofac Surg Clin North Am. 2007 May;19(2):153-62, v. doi: 10.1016/j.coms.2007.01.009.

DOI:10.1016/j.coms.2007.01.009

PMID:18088874

Abstract

This article focuses on the pathogenesis of the gender gap of autoimmune disease. Specifically, the discussion characterizes the role of sex hormones in the immune response and a female predilection for the common diseases seen in daily practice (ie, lupus erythematosus, myasthenia gravis, and other autoimmune diseases). A comparison between the sexes, with respect to autoimmune disease mechanisms, is presented to give oral and maxillofacial surgeons a better insight as to the role of sex and successful surgical treatment outcomes in this population of patients.

摘要

本文聚焦于自身免疫性疾病性别差异的发病机制。具体而言，该讨论阐述了性激素在免疫反应中的作用以及女性在日常临床中常见疾病（如红斑狼疮、重症肌无力和其他自身免疫性疾病）中的易感性。文中对两性在自身免疫性疾病机制方面进行了比较，以便让口腔颌面外科医生更好地了解性别在这类患者群体中的作用以及手术治疗的成功效果。