Lima Isabella, Melo Ailton, Brandi Ivar Viana, Costa Olívia, Santiago Mittermayer
Serviço de Reumatologia do Hospital Santa Izabel (HSI), Salvador, Bahia, Brazil.
J Clin Rheumatol. 2007 Apr;13(2):85-6. doi: 10.1097/01.rhu.0000260637.95695.40.
A multiple sclerosis-like syndrome, also called lupoid sclerosis for having some lupus characteristics, has been described in a few reports. Recently, antiphospholipid antibodies have been demonstrated in patients with this syndrome, suggesting that they can participate in the etiopathogenic process, which can have therapeutic implications. We report the case of a patient previously diagnosed with multiple sclerosis who later presented with ANA positivity and antiphospholipid antibodies, livedo reticularis, and deep venous thrombosis, leading her to be characterized as having lupoid sclerosis. The patient was anticoagulated. Antiphospholipid antibodies may be involved in the pathogenesis of lupoid sclerosis.
一种多发性硬化样综合征，因其具有一些狼疮特征也被称为类狼疮性硬化，已在一些报告中有所描述。最近，在患有这种综合征的患者中已证实存在抗磷脂抗体，这表明它们可能参与发病机制过程，这可能具有治疗意义。我们报告了一例先前被诊断为多发性硬化的患者，该患者后来出现抗核抗体阳性、抗磷脂抗体、网状青斑和深静脉血栓形成，从而被诊断为类狼疮性硬化。该患者接受了抗凝治疗。抗磷脂抗体可能参与类狼疮性硬化的发病机制。
