Alessi Daniela, Pastore Guido, Zuccolo Luisa, Mosso Maria Luisa, Richiardi Lorenzo, Pearce Neil, Magnani Corrado, Merletti Franco
Childhood Cancer Registry of Piedmont, Cancer Epidemiology Unit, CeRMS and CPO-Piemonte, University of Turin, Torino, Italy.
Eur J Cancer Prev. 2007 Dec;16(6):576-80. doi: 10.1097/CEJ.0b013e32801023ee.
The aim of this study was to compare the characteristics of respondents and nonrespondents in a survey of childhood cancer survivors recorded in the Childhood Cancer Registry of Piedmont and their current primary care general practitioners. Eligible subjects were identified from the Childhood Cancer Registry of Piedmont and the referring general practitioners were traced through the National Health Service. A postal questionnaire was sent both to childhood cancer survivors and to their general practitioners. Prevalence odds ratios were estimated for demographic and clinical characteristics in survivors and for demographic characteristics in general practitioners. A total of 1005 childhood cancer survivors and 857 general practitioners (132 of them had two or more cancer survivors in care) were included in the study. Completed questionnaires were obtained from 691 survivors (69%) and 615 general practitioners (72%). For survivors, the only associations with nonresponse were for age 35-44 years [prevalence odds ratio: 0.53 (95% confidence interval: 0.33-0.85)], being married [prevalence odds ratio: 1.45 (95% confidence interval: 0.96-2.18)] and diagnosis after 1977 [prevalence odds ratio: 0.66 (95% confidence interval: 0.42-1.03)]. For general practitioners, the only associations were for male sex [prevalence odds ratio: 1.62 (95% confidence interval: 1.13-2.32)] and place of work outside of the city of Turin [prevalence odds ratio: 1.93 (95% confidence interval: 1.07-3.47)]; furthermore associations were relatively weak. An association was also found between nonresponse in survivors and nonresponse in their general practitioners [prevalence odds ratio: 3.40 (95% confidence interval: 2.54-4.56)]. In conclusion, apart from age, marital status and period of diagnosis, there were little differences between respondent and nonrespondents, for the considered clinical and demographical characteristics. Participation of survivors and their general practitioners correlated, suggesting that involvement of the general practitioners in the study may be a method to increase participation of survivors of childhood cancers.
本研究旨在比较皮埃蒙特儿童癌症登记处记录的儿童癌症幸存者及其当前初级保健全科医生调查中应答者和非应答者的特征。符合条件的受试者从皮埃蒙特儿童癌症登记处中确定，并通过国家医疗服务体系追踪转诊的全科医生。向儿童癌症幸存者及其全科医生发送了邮政问卷。估计了幸存者的人口统计学和临床特征以及全科医生的人口统计学特征的患病率比值比。共有1005名儿童癌症幸存者和857名全科医生（其中132名照顾两名或更多癌症幸存者）纳入研究。从691名幸存者（69%）和615名全科医生（72%）处获得了完整问卷。对于幸存者，与未应答相关的唯一因素是年龄35 - 44岁[患病率比值比：0.53（95%置信区间：0.33 - 0.85）]、已婚[患病率比值比：1.45（95%置信区间：0.96 - 2.18）]以及1977年后诊断[患病率比值比：0.66（95%置信区间：0.42 - 1.03）]。对于全科医生，唯一的相关因素是男性[患病率比值比：1.62（95%置信区间：1.13 - 2.32）]和在都灵市以外的工作地点[患病率比值比：1.93（95%置信区间：1.07 - 3.47）]；此外，相关性相对较弱。还发现幸存者未应答与其全科医生未应答之间存在关联[患病率比值比：3.40（95%置信区间：2.54 - 4.56）]。总之，除年龄、婚姻状况和诊断时期外，就所考虑的临床和人口统计学特征而言，应答者和非应答者之间差异不大。幸存者及其全科医生的参与具有相关性，这表明全科医生参与研究可能是增加儿童癌症幸存者参与度的一种方法。
