Chervu I, Koss M, Campese V M
Department of Medicine, University of Southern California, Los Angeles.
Am J Nephrol. 1991;11(5):411-5. doi: 10.1159/000168348.
Two patients who developed bilateral renal cortical necrosis as a consequence of Neisseria meningitidis infections are described: 1 patient had meningococcemia and the other had meningococcal meningitis. Both patients developed a Shwartzman-like reaction, disseminated intravascular coagulation and irreversible renal failure. Renal biopsy showed sclerosis of the majority of glomeruli; some glomeruli showed capillary congestion, thrombosis and an increased number of neutrophils; the intralobular arterioles showed thrombotic occlusions.
1例患有脑膜炎球菌血症,另1例患有脑膜炎球菌性脑膜炎。两名患者均出现了类施瓦茨曼反应、弥散性血管内凝血和不可逆的肾衰竭。肾活检显示大多数肾小球硬化;一些肾小球显示毛细血管充血、血栓形成和中性粒细胞数量增加;小叶内小动脉显示血栓性闭塞。