Semple John L
Toronto, Ontario, Canada From the Division of Plastic Surgery, Women's College Hospital, and the Department of Surgery, University of Toronto.
Plast Reconstr Surg. 2007 Dec;120(7 Suppl 1):123S-128S. doi: 10.1097/01.prs.0000286579.27852.ed.
Despite the overwhelming advantages of breast-feeding, there is a persistent concern that maternal exposure to chemical contaminants may result in contamination of breast milk and have an effect on the child's growth and development. A parallel concern regarding lactation in women with silicone implants over the past years has led to confusion and anxiety relating to the potential risks to the child.
The author reviewed the facts and issues as he knows them, including biomaterials, lactation toxicology, and a previous study where no difference was found in silicon (a proxy measurement of silicone) in women breast-feeding with silicone implants and those without.
In the author's previous study, he compared women with implants to women without implants as controls and showed that mean silicon levels were not significantly different in breast milk (55.45 +/- 35 and 51.05 +/- 31 ng/ml, respectively) or in blood (79.29 +/- 87 and 103.76 +/- 112 ng/ml, respectively). However, silicon levels in alternative methods of infant nutrition were much higher. The mean silicon level measured in store-bought cow's milk was 708.94 ng/ml, whereas that for 26 brands of commercially available infant formula was 4402.5 ng/ml.
In this review, the author looked only at silicon/silicone and did not address other potential contaminants that may be associated with silicone gel or the elastomer shell. This report may provide plastic surgeons and other healthcare workers with information regarding silicon/silicone for discussion with women with gel implants who are contemplating breast-feeding.
尽管母乳喂养具有诸多显著优势,但人们一直担心母亲接触化学污染物可能导致母乳受到污染,并影响孩子的生长发育。过去几年,对于植入硅胶的女性哺乳问题的类似担忧,引发了关于对孩子潜在风险的困惑和焦虑。
作者回顾了他所了解的事实和问题,包括生物材料、哺乳毒理学,以及一项先前的研究,该研究发现植入硅胶的母乳喂养女性和未植入硅胶的母乳喂养女性的硅(硅胶的替代测量指标)含量没有差异。
在作者先前的研究中,他将植入硅胶的女性与未植入硅胶的女性作为对照进行比较,结果显示母乳中的平均硅含量(分别为55.45±35和51.05±31纳克/毫升)或血液中的平均硅含量(分别为79.29±87和103.76±112纳克/毫升)没有显著差异。然而,婴儿其他营养方式中的硅含量要高得多。市售牛奶中测得的平均硅含量为708.94纳克/毫升,而26个品牌的市售婴儿配方奶粉中的平均硅含量为4402.5纳克/毫升。
在本综述中,作者仅关注了硅/硅胶,并未涉及可能与硅胶凝胶或弹性体外壳相关的其他潜在污染物。本报告可为整形外科医生和其他医护人员提供有关硅/硅胶的信息,以便与考虑母乳喂养的植入凝胶假体的女性进行讨论。