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增强型体外反搏(EECP)对心肌灌注的影响。

Effects of enhanced external counterpulsation (EECP) on myocardial perfusion.

作者信息

Arora Rohit R, Bergmann Steven

机构信息

Department of Medicine, Chicago Medical School, Chicago, Illinois 60064, USA.

出版信息

Am J Ther. 2007 Nov-Dec;14(6):519-23. doi: 10.1097/01.mjt.0000249890.00290.30.

Abstract

PURPOSE

To evaluate whether enhanced external counterpulsation (EECP) exerts an effect on myocardial perfusion.

METHODS

Eleven patients with angina were studied before and after 35 sessions of EECP treatment. Myocardial perfusion was quantified with positron emission tomography and intravenous 13N-ammonia at rest and after dipyridamole, by means of a two-compartment mathematical model.

CONCLUSION

The results suggest that EECP has no effect on myocardial perfusion. However, because of the small number of patients in this study and highly variable clinical responses, additional studies are required to corroborate this finding. The beneficial effects of EECP appear to be mediated by other mechanisms.

摘要

目的

评估增强型体外反搏(EECP)是否对心肌灌注有影响。

方法

对11例心绞痛患者在进行35次EECP治疗前后进行研究。通过两室数学模型,利用正电子发射断层扫描和静脉注射13N-氨,在静息状态和双嘧达莫给药后对心肌灌注进行定量分析。

结论

结果表明EECP对心肌灌注无影响。然而,由于本研究中的患者数量较少且临床反应差异很大,需要进一步的研究来证实这一发现。EECP的有益作用似乎是由其他机制介导的。

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