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增强型体外反搏对难治性心绞痛患者血压的影响。

Effects on blood pressure in patients with refractory angina pectoris after enhanced external counterpulsation.

作者信息

Bondesson Susanne, Pettersson Thomas, Ohlsson Ola, Hallberg Ingalill R, Wackenfors Angelica, Edvinsson Lars

机构信息

Department of Medicine, Kristianstad, Sweden.

出版信息

Blood Press. 2010 Oct;19(5):287-94. doi: 10.3109/08037051003794375.

Abstract

OBJECTIVE

Enhanced external counterpulsation (EECP) is a non-invasive technique that has been shown to reduce the frequency and severity of angina pectoris. Little is known how EECP affects the blood pressure.

METHODS

153 patients with refractory angina were treated with either EECP or retained on their pharmacological treatment (reference group). Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP) and heart rate were measured pre- and post-treatment and at 12 months follow-up.

RESULTS

EECP treatment altered the blood pressure in patients with refractory angina pectoris. A decrease in the blood pressure was more common in the EECP group compared with the reference group. In the reference group, an increase in the blood pressure was more common. A correlation between a decrease in blood pressure after EECP treatment and a higher baseline MAP, SBP and DBP was seen. No such correlation was seen in the reference group. The blood pressure response did not persist at 12 months follow-up.

CONCLUSION

EECP treatment affects the blood pressure in patients with refractory angina pectoris. The decreased blood pressure may be a result of an improved exercise capacity, an improved endothelial function and vasoreactivity in general.

摘要

目的

增强型体外反搏(EECP)是一种已被证明可降低心绞痛发作频率和严重程度的非侵入性技术。关于EECP如何影响血压,人们知之甚少。

方法

153例难治性心绞痛患者接受EECP治疗或继续其药物治疗(参照组)。在治疗前、治疗后以及随访12个月时测量收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)和心率。

结果

EECP治疗改变了难治性心绞痛患者的血压。与参照组相比,EECP组血压下降更为常见。在参照组中,血压升高更为常见。观察到EECP治疗后血压下降与较高的基线MAP、SBP和DBP之间存在相关性。在参照组中未观察到这种相关性。血压反应在随访12个月时未持续存在。

结论

EECP治疗会影响难治性心绞痛患者的血压。血压下降可能是运动能力改善、内皮功能改善以及总体血管反应性改善的结果。

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