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术前化疗及术中射频消融治疗不可切除的胰腺实性假乳头状瘤

Preoperative chemotherapy and intraoperative radiofrequency ablation for unresectable solid pseudopapillary tumor of the pancreas.

作者信息

Hah Jeong Ok, Park Won Kyu, Lee Nam Hyuk, Choi Joon Hyuk

机构信息

Department of Pediatrics, College of Medicine, Yeungnam University, Daegu, Korea.

出版信息

J Pediatr Hematol Oncol. 2007 Dec;29(12):851-3. doi: 10.1097/MPH.0b013e318158159c.

Abstract

Solid pseudopapillary tumor (SPT) is rare primary tumor of the pancreas with low malignant potential affecting adolescent or young women. Radical surgical resection is the definitive treatment for long-term survival even in the patients with metastases. We report a case of 14-year-old girl who presented with unresectable SPT of the pancreas. She received preoperative chemotherapy with cisplatinum, ifosfamide, etoposide, and vincristine followed by intraoperative radiofrequency ablation of metastatic liver lesions with surgical resection of the primary tumor successfully. We demonstrate that all attempts should be made to resect or ablate the primary as well as the metastatic lesions for long-term survival.

摘要

实性假乳头状瘤(SPT)是一种罕见的胰腺原发性肿瘤,恶性潜能低,主要影响青少年或年轻女性。根治性手术切除是实现长期生存的确定性治疗方法,即使是对有转移的患者也是如此。我们报告一例14岁女孩,她患有无法切除的胰腺SPT。她接受了顺铂、异环磷酰胺、依托泊苷和长春新碱的术前化疗,随后对转移性肝病灶进行术中射频消融,并成功切除了原发性肿瘤。我们证明,为了实现长期生存,应尽一切努力切除或消融原发性和转移性病灶。

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