Gao Ying, Wu Lingling, Li Aijun
Peking University Third Hospital, Peking University Eye Center, Beijing, China.
J Glaucoma. 2007 Oct-Nov;16(7):594-7. doi: 10.1097/IJG.0b013e318064c818.
To determine and compare the daily cost of various glaucoma medications in China.
The majority of glaucoma medications commercially available in China were included in this research. The total number of drops in 1 bottle of each medication was counted drop by drop. The mean volume per bottle of each medication was calculated. The cost per drop, number of days for both eyes usage per bottle, and daily cost was calculated.
(1) The volume per drop ranged from 0.03 mL (brinzolamide 1%, travoprost 0.004%, bimatoprost 0.03%, and latanoprost 0.005%) to 0.05 mL (timolol 0.5%-Chengrui and pilocarpine 0.5% and 2%-Zhenrui). (2) The cost per bottle ranged from $0.69 (US dollar) (timolol 0.5%-Malaisuan Saimaluo'er) to $40.78 (latanoprost 0.005%). (3) The number of days for both eyes usage per bottle ranged from 52 days (bimatoprost 0.03%) to 11 days (pilocarpine nitrate 0.5%-Zhenrui). (4) The daily cost for both eyes usage from expensive to cheap were latanoprost 0.005%-$0.91, travoprost 0.004%-$0.77, brimonidine 0.2%-$0.61, bimatoprost 0.03%-$0.46, D-timolol 1%-$0.36, brinzolamide 1%-$0.34, pilocarpine 2%-Zhenrui-$0.28, levobunolol 0.5%-$0.25, betaxolol 0.25%-$0.24, pilocarpine 0.5%-Zhenrui-$0.18, pilocarpine 2%-Huming-$0.16, carteolol 1%-Mikelan-$0.15, carteolol 2%-Mikelan-$0.15, pilocarpine 1%-Huming-$0.10, timolol 0.5%-Chengrui-$0.08, timolol 0.5%-Malaisuan Saimaluo'er-$0.03.
The daily cost of glaucoma medications in China ranged much more wildly than developed countries. These data may be useful in selecting medications for glaucoma therapy. The ophthalmic solution of prostaglandins is powerful in reducing intraocular pressure. However, its high price should be considered when selecting glaucoma medications in China.
确定并比较中国各种青光眼药物的每日费用。
本研究纳入了中国市场上大多数可买到的青光眼药物。逐滴清点每瓶每种药物的总滴数。计算每种药物每瓶的平均体积。计算每滴成本、每瓶药物双眼使用天数以及每日费用。
(1)每滴体积范围从0.03毫升(1%布林佐胺、0.004%曲伏前列素、0.03%比马前列素和0.005%拉坦前列素)到0.05毫升(0.5%噻吗洛尔 - 诚瑞和0.5%及2%毛果芸香碱 - 珍瑞)。(2)每瓶成本范围从0.69美元(0.5%噻吗洛尔 - 马来酸噻吗洛尔)到40.78美元(0.005%拉坦前列素)。(3)每瓶药物双眼使用天数范围从52天(0.03%比马前列素)到11天(0.5%硝酸毛果芸香碱 - 珍瑞)。(4)双眼使用的每日费用从高到低依次为:0.005%拉坦前列素 - 0.91美元、0.004%曲伏前列素 - 0.77美元、0.2%溴莫尼定 - 0.61美元、0.03%比马前列素 - 0.46美元、1%右旋噻吗洛尔 - 0.36美元、1%布林佐胺 - 0.34美元、2%珍瑞毛果芸香碱 - 0.28美元、0.5%左布诺洛尔 - 0.25美元、0.25%倍他洛尔 - 0.24美元、0.5%珍瑞毛果芸香碱 - 0.18美元、2%沪明毛果芸香碱 - 0.16美元、1%米开郎卡替洛尔 - 0.15美元、2%米开郎卡替洛尔 - 0.15美元、1%沪明毛果芸香碱 - 0.10美元、0.5%噻吗洛尔 - 诚瑞 - 0.08美元、0.5%噻吗洛尔 - 马来酸噻吗洛尔 - 0.03美元。
中国青光眼药物的每日费用比发达国家差异大得多。这些数据可能有助于选择青光眼治疗药物。前列腺素类眼药水降低眼压效果显著。然而,在中国选择青光眼药物时应考虑其高昂价格。