Mendoza Vinia, Vahid Bobbak, Kozic Heidic, Weibel Sandra
Thomas Jefferson University, Department of Medicine, Philadelphia, USA.
Joint Bone Spine. 2007 Dec;74(6):647-9. doi: 10.1016/j.jbspin.2006.12.007.
Necrobiosis lipoidica dibeticum (NLD) is a granulomatous skin disease mostly associated with diabetes mellitus. NLD has been reported in patients with other systemic disease. Also, the lesions of NLD may be clinically, and sometimes even histologically indistinguishable from other inflammatory skin lesions. We described three patients with established diagnosis of sarcoidosis that developed skin lesions consistent with NLD. The association of NLD-like skin lesion in sarcoidosis is not widely appreciated. The subject of NLD and sarcoidosis is reviewed.
糖尿病性类脂质渐进性坏死（NLD）是一种主要与糖尿病相关的肉芽肿性皮肤病。NLD在患有其他全身性疾病的患者中也有报道。此外，NLD的皮损在临床上，有时甚至在组织学上都可能与其他炎症性皮肤病变难以区分。我们描述了3例已确诊结节病且出现与NLD一致的皮肤病变的患者。结节病中类似NLD的皮肤病变之间的关联尚未得到广泛认识。本文对NLD和结节病的相关内容进行了综述。
