Blevins Maryellen
Samaritan Medical Center, Watertown, NY, USA.
Int J Low Extrem Wounds. 2023 Mar;22(1):185-189. doi: 10.1177/1534734621999269. Epub 2021 Mar 20.
Necrobiosis lipoidica is a granulomatous skin condition commonly associated with diabetes. When associated with diabetes mellitus, the name expands to necrobiosis lipoidica diabeticorum (NLD). In these patients, this rare condition has an incidence rate of 0.3% to 1.6%. The cause of NLD remains unknown even though many speculations exist in the medical literature. The treatment of this condition has most researchers agreeing on the use of topical steroids for the anti-inflammatory effect on NLD; however, the role of glucose control in the treatment of this disorder has been debatable. The following case presents a patient who, despite better glucose control, did not improve until the introduction of doxycycline.
类脂质渐进性坏死是一种通常与糖尿病相关的肉芽肿性皮肤病。当与糖尿病相关时，其名称扩展为糖尿病性类脂质渐进性坏死（NLD）。在这些患者中，这种罕见疾病的发病率为0.3%至1.6%。尽管医学文献中有许多推测，但NLD的病因仍然不明。对于这种疾病的治疗，大多数研究人员都同意使用外用类固醇来对NLD产生抗炎作用；然而，血糖控制在这种疾病治疗中的作用一直存在争议。以下病例介绍了一位患者，尽管血糖控制有所改善，但在引入强力霉素之前病情并未好转。
