Hussain Farrukh, Philipp Roger, Zieroth Shelley
Int J Cardiol. 2009 Mar 20;133(1):e11-3. doi: 10.1016/j.ijcard.2007.08.078. Epub 2008 Feb 21.
Heparin induced thrombocytopenia and thrombosis (HITT) syndrome is a rare but potentially life threatening disorder, which is increasingly recognized with the widespread use of heparin. We report a rare case of early stent thrombosis secondary to HITT in a patient initially presenting with cardiogenic shock, which occurred 9 days after primary bare metal stent implantation due to subcutaneous heparin exposure. The most important factor in detection of HITT remains a high index of clinical suspicion and close monitoring of the temporal trend of thrombocytopenia, particularly when trying to distinguish HITT from other sources of thrombocytopenia seen in critically ill patients.
肝素诱导的血小板减少症和血栓形成（HITT）综合征是一种罕见但可能危及生命的疾病，随着肝素的广泛使用，其越来越受到认可。我们报告了一例罕见的因HITT继发早期支架血栓形成的病例，该患者最初表现为心源性休克，在因皮下皮下暴露接受皮下肝素治疗后，于初次植入裸金属支架9天后发生了这种情况。检测HITT的最重要因素仍然是高度的临床怀疑以及密切监测血小板减少症的时间趋势，尤其是在试图将HITT与重症患者中出现的其他血小板减少症来源进行区分时。
