Heparin-induced thrombocytopenia and thrombosis: a case study and clinical overview.

PURPOSE/OBJECTIVES: To describe the mechanisms and nursing care associated with heparin-induced thrombocytopenia and thrombosis (HITT).

DATA SOURCES

Published books and journal articles as well as clinical experience.

DATA SYNTHESIS

HITT is an immune reaction that occurs in 1%-10% of individuals receiving heparin therapy. Characterized by a sudden drop in platelets, it can result in life-threatening hemorrhage and thrombus-related events.

CONCLUSIONS

Heparin commonly is used in many oncology treatment settings. Awareness of this potentially serious complication and knowledge of its treatment is critical to safe administration.

IMPLICATIONS FOR NURSING PRACTICE

Astute assessment skills are the key to diagnosis and treatment of HITT.