Cochat Pierre, Badet Lionel
Département de pédiatrie, hôpital Edouard-Herriot, université Lyon- Lyon cedex, France.
Nephrol Ther. 2008 Feb;4(1):77-80. doi: 10.1016/j.nephro.2007.07.019.
Living-donor transplantation has several obvious advantages for children: better graft-survival than cadaveric-transplantation, the possibility to be pre-emptive and avoid dialysis and its burden to the child, to be programmed during school holidays. However, its negative aspects must not be ignored. They are mainly psychological and concern the adolescent. The affective burden of both living-donation and transplantation is so strong that a psychological check-up is mandatory for the donor but also for the recipient and even the non-donor parent. In the medical evaluation of the donor, specific explorations, such as the search of a genetic mutation, could be necessary in the case of hereditary renal disease.
移植存活率高于尸体移植,有可能进行预防性移植,避免透析及其给儿童带来的负担,还可以安排在学校假期进行。然而,其负面影响也不容忽视。这些影响主要是心理方面的,且涉及青少年。活体捐赠和移植带来的情感负担非常强烈,因此不仅对供体,对受体甚至非供体父母都必须进行心理检查。在对供体进行医学评估时,对于遗传性肾病患者,可能需要进行特定的检查,如寻找基因突变。