Saceda-Gutiérrez J M, Isla-Guerrero A J, Pérez-López C, Ortega-Martínez R, Gómez de la Riva A, Gandia-González M L, Gutiérrez-Molina M, Rey-Herranz J A
Servicios Neurocirugía, Hospital Universitario La Paz, Madrid.
Neurocirugia (Astur). 2007 Dec;18(6):496-504.
We report 3 patients with fibrous solitary tumor of meningeal location where we described the histological study, as well as evolution after the surgical treatment. The described patients presented ages of 37, 52 and 65 years, after the resection has not appeared an objective sign of recurrence in any case after 4, 6 and 7 years of follow-up respectively. Checking the literature the tumor is indistinguishable clinical and radiolocally of the typical meningioma, doing necessary the use of inmunohistochemistry to do the differential diagnosis, where positiveness for CD34 and the negativeness for EMA define the fibrous solitary tumor. It is about a benign tumor, where total removing is the principal factor in prognosis, nevertheless there are cases of local recurrences and long-distance metastasis. We can find all these characteristics in the showed cases of the present article, having the uncertainty of its local or systemic relapse ability in the future.
我们报告了3例脑膜部位的纤维性孤立性肿瘤患者，描述了其组织学研究以及手术治疗后的病情演变。所描述的患者年龄分别为37岁、52岁和65岁，切除术后分别经过4年、6年和7年的随访，均未出现复发的客观迹象。查阅文献发现，该肿瘤在临床和影像学上与典型脑膜瘤难以区分，因此有必要使用免疫组织化学进行鉴别诊断，其中CD34阳性和EMA阴性可确诊为纤维性孤立性肿瘤。这是一种良性肿瘤，手术全切是预后的主要因素，不过仍有局部复发和远处转移的病例。在本文所展示的病例中均可发现这些特征，其未来局部或全身复发的可能性尚不确定。
