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直肠前切除术后吻合口漏的内镜下真空辅助闭合:一种新方法。

Endoscopic vacuum-assisted closure of anastomotic leakage following anterior resection of the rectum: a new method.

作者信息

Weidenhagen Rolf, Gruetzner Klaus Uwe, Wiecken Timm, Spelsberg Fritz, Jauch Karl-Walter

机构信息

Department of Surgery, Klinikum Grosshadern, Ludwig-Maximilian-University of Munich, Marchioninistr, 15, D-81377, Munich, Germany.

出版信息

Surg Endosc. 2008 Aug;22(8):1818-25. doi: 10.1007/s00464-007-9706-x. Epub 2007 Dec 20.

Abstract

BACKGROUND

Conservative treatment of anastomotic leakage after anterior resection of the rectum seems to be possible in patients who have no occurrence of generalized peritonitis. This report describes a new method of endoscopic management of large anastomotic leakage in these patients.

METHOD

The main feature of this new method is the endoscopically assisted placement of an open-cell sponge connected to a vacuum device into the abscess cavity via an introducer device. The sponge system is changed every 48-72 h.

RESULTS

Twenty-nine patients with an anastomotic leakage after anterior resection were treated with the endoscopic vacuum therapy. The total duration of endovac therapy was 34.4 +/- 19.4 days. The total number of endoscopic sessions per patient was 11.4 +/- 6.3. In 21 of the 29 patients, a protecting stoma was created at the primary operation. Four patients were treated successfully without the need of a secondary stoma. Definitive healing was achieved in 28 of the 29 patients.

CONCLUSIONS

Endoscopic vacuum-assisted closure is a new efficacious modality for treating anastomotic leakage following anterior resection due to an effective control of the septic focus. Further studies will show if it is possible to reduce the high mortality rate of patients with anastomotic leakage through the avoidance of surgical reinterventions while at the same time preserving the sphincter function.

摘要

背景

对于未发生全身性腹膜炎的直肠前切除术后吻合口漏患者,似乎可以采用保守治疗。本报告描述了一种针对这些患者大吻合口漏的内镜处理新方法。

方法

这种新方法的主要特点是通过导入装置在内镜辅助下将连接真空装置的开孔海绵置入脓肿腔。海绵系统每48 - 72小时更换一次。

结果

29例直肠前切除术后吻合口漏患者接受了内镜真空治疗。内镜真空治疗的总时长为34.4 ± 19.4天。每位患者的内镜治疗总次数为11.4 ± 6.3次。29例患者中有21例在初次手术时造了保护性造口。4例患者无需二次造口即成功治愈。29例患者中有28例实现了最终愈合。

结论

内镜真空辅助闭合术是治疗直肠前切除术后吻合口漏的一种新的有效方式,因为它能有效控制感染灶。进一步的研究将表明,通过避免手术再次干预,同时保留括约肌功能,是否有可能降低吻合口漏患者的高死亡率。

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