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[一例以双侧听力丧失为表现的脑膜癌病]

[A case of meningeal carcinomatosis presenting with bilateral hearing loss].

作者信息

Okamoto Yoko, Sugiyama Hiromichi, Yamamoto Toru

机构信息

Department of Neurology, Osaka Saiseikai Nakatsu Hospital, Japan.

出版信息

Brain Nerve. 2007 Dec;59(12):1385-9.

Abstract

We report the case of a 63-year-old male who developed rapidly progressive bilateral deafness. Two months later he became stuporous, and was transferred to our hospital. The patient's MRI demonstrated bilateral hypertrophic VII-VIII cranial nerve roots that were well enhanced. Gradually, the patient's condition worsened, and he died on the 12th day after admission. Autopsy revealed meningeal carcinomatosis with poorly differentiated gastric adenocarcinoma. White firm masses of the bilateral seventh and eighth bilateral cranial nerve roots were found at autopsy, which were found to be metastases of the gastric cancer cells as well. Metastatic tumors can be take into consideration as a differential diagnosis for bilateral-enhanced eighth cranial nerve root masses.

摘要

我们报告了一例63岁男性患者,其出现快速进展的双侧耳聋。两个月后,他陷入昏迷,并被转至我院。患者的MRI显示双侧VII - VIII颅神经根肥厚且强化良好。逐渐地,患者病情恶化,入院后第12天死亡。尸检发现脑膜癌病伴低分化胃腺癌。尸检时在双侧第七和第八颅神经根处发现白色坚实肿块,这些肿块也被发现是胃癌细胞的转移灶。转移性肿瘤可作为双侧强化的第八颅神经根肿块的鉴别诊断考虑因素。

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