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The GPCR modulator protein RAMP2 is essential for angiogenesis and vascular integrity.
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Blood is thicker than lymph.
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Adrenomedullin signaling is necessary for murine lymphatic vascular development.
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Vascular endothelial adrenomedullin-RAMP2 system is essential for vascular integrity and organ homeostasis.
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Regulation of cardiovascular development and homeostasis by the adrenomedullin-RAMP system.
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Shared and separate functions of the RAMP-based adrenomedullin receptors.
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The endothelial adrenomedullin-RAMP2 system regulates vascular integrity and suppresses tumour metastasis.
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Novel regulation of cardiac metabolism and homeostasis by the adrenomedullin-receptor activity-modifying protein 2 system.
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Apelin-13 modulates the endometrial transcriptome of the domestic pig during implantation.
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Clinical Potential of Adrenomedullin Signaling in the Cardiovascular System.
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Enhanced external counterpulsation improves dysfunction of forearm muscle caused by radial artery occlusion.
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Role of adrenomedullin2/ intermedin in pregnancy induced vascular and metabolic adaptation in mice.
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Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age.
J Biol Chem. 2007 Jun 22;282(25):18094-18099. doi: 10.1074/jbc.M703544200. Epub 2007 Apr 30.
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Adrenomedullin insufficiency increases allergen-induced airway hyperresponsiveness in mice.
J Appl Physiol (1985). 2007 Jun;102(6):2361-8. doi: 10.1152/japplphysiol.00615.2006. Epub 2007 Mar 1.
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RAMPs: The past, present and future.
Trends Biochem Sci. 2006 Nov;31(11):631-8. doi: 10.1016/j.tibs.2006.09.006. Epub 2006 Sep 28.
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Cardiac adrenomedullin: its role in cardiac hypertrophy and heart failure.
Curr Med Chem Cardiovasc Hematol Agents. 2005 Jul;3(3):231-42. doi: 10.2174/1568016054368241.
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Adrenomedullin: angiogenesis and gene therapy.
Am J Physiol Regul Integr Comp Physiol. 2005 Jun;288(6):R1432-7. doi: 10.1152/ajpregu.00662.2004.
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Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking.
J Biol Chem. 2005 Mar 11;280(10):9297-307. doi: 10.1074/jbc.M413786200. Epub 2004 Dec 21.
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Adrenomedullin enhances therapeutic potency of bone marrow transplantation for myocardial infarction in rats.
Am J Physiol Heart Circ Physiol. 2005 Mar;288(3):H1444-50. doi: 10.1152/ajpheart.00266.2004. Epub 2004 Nov 11.
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Adrenomedullin receptors: pharmacological features and possible pathophysiological roles.
Peptides. 2004 Nov;25(11):2003-12. doi: 10.1016/j.peptides.2004.06.002.
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Angiogenic effects of adrenomedullin in ischemia and tumor growth.
Circ Res. 2004 Aug 20;95(4):415-23. doi: 10.1161/01.RES.0000138018.61065.d1. Epub 2004 Jul 8.

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