Ramachandran P, Gupta A, Vincent P, Sridharan S
Department of Pediatric Surgery, Kanchi Kamakoti Child's Trust Hospital, 12-A, Nageswara Road, Nungambakkam, Chennai 600034, India.
Pediatr Surg Int. 2008 Mar;24(3):311-3. doi: 10.1007/s00383-007-2101-9. Epub 2007 Dec 21.
Air enema is the treatment of choice for childhood intussusceptions. Although peritonitis is the established contraindication, studies have attempted to identify factors that affect the outcome of air enema. In our series we studied the impact of such factors on the clinical scenario to determine if it was important to predict the outcome of air enema. We retrospectively reviewed the records of 179 children who underwent air enema for intussusception at our institution over a 5-year period. Abdominal colic was present in 144 children, vomiting in 139 and rectal bleeding in 108 children. The duration of symptoms was less than 24 h in 131 children. An abdominal mass was present in 121 children, rectal prolapse of intussusception in 14, dehydration in 31 and small bowel obstruction in 27 children. The success rate of air enema was calculated. All clinical features were analyzed for impact on outcome using univariate and multivariate analysis. The extent of this impact on the clinical scenario was examined. Air enema was successful in 157 cases (89%). One child developed a perforation during the procedure (0.6%). The recurrence rate was 8%. Using chi2 test, success of air enema was reduced in the presence of rectal bleeding, rectal prolapse of intussusception, dehydration, and small bowel obstruction. This reduction was statistically significant (P < 0.05). Using logistic regression analysis, the success of air enema was significantly reduced (P < 0.05) only in the presence of prolapsing rectal intussusception (57%) and small bowel obstruction (52%). Small bowel obstruction and prolapsing rectal intussusceptions merely reduce the success of air enema and do not increase the complications. Since the success of air enema is very high, it must be attempted in all children with the exception of peritonitis. Predicting the outcome is not crucial because of the high success rate and low complication rate.
空气灌肠是小儿肠套叠的首选治疗方法。尽管腹膜炎是公认的禁忌证,但已有研究试图确定影响空气灌肠治疗效果的因素。在我们的研究系列中,我们研究了这些因素对临床情况的影响,以确定预测空气灌肠治疗效果是否重要。我们回顾性分析了我院5年间179例行空气灌肠治疗肠套叠患儿的病历。144例患儿有腹部绞痛,139例有呕吐,108例有直肠出血。131例患儿症状持续时间小于24小时。121例患儿可触及腹部肿块,14例有肠套叠直肠脱垂,31例有脱水,27例有小肠梗阻。计算空气灌肠的成功率。采用单因素和多因素分析方法分析所有临床特征对治疗效果的影响。研究了这种影响在临床情况中的程度。空气灌肠成功157例(89%)。1例患儿在操作过程中发生穿孔(0.6%)。复发率为8%。采用卡方检验,存在直肠出血、肠套叠直肠脱垂、脱水和小肠梗阻时,空气灌肠成功率降低。这种降低具有统计学意义(P<0.05)。采用逻辑回归分析,仅在存在脱垂性直肠套叠(57%)和小肠梗阻(52%)时,空气灌肠成功率显著降低(P<0.05)。小肠梗阻和脱垂性直肠套叠仅降低空气灌肠成功率,并不会增加并发症。由于空气灌肠成功率很高,除腹膜炎患儿外,所有患儿均应尝试进行空气灌肠。由于成功率高且并发症率低,预测治疗效果并不关键。