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球囊在小儿肠套叠空气灌肠复位中应用的安全性和有效性比较

Comparative safety and efficacy of balloon use in air enema reduction for pediatric intussusception.

作者信息

Golriz Farahnaz, Cassady Christopher I, Bales Brandy, Herrejon Christi, Hicks M John, Zhang Wei, Orth Robert C, Guillerman R Paul

机构信息

Edward B. Singleton Department of Pediatric Radiology, Texas Children's Hospital, 6701 Fannin St., Suite 470, Houston, TX, 77030, USA.

Department of Pathology, Texas Children's Hospital, Houston, TX, USA.

出版信息

Pediatr Radiol. 2018 Sep;48(10):1423-1431. doi: 10.1007/s00247-018-4156-2. Epub 2018 May 24.

DOI:10.1007/s00247-018-4156-2
PMID:29797036
Abstract

BACKGROUND

Intussusception, a common cause of bowel obstruction in young children, is primarily treated with air enema reduction. There is little literature comparing the safety and efficacy of air reduction without or with a rectal balloon.

OBJECTIVE

To determine the safety and efficacy of a rectal balloon seal in air enema reduction.

MATERIALS AND METHODS

We retrospectively reviewed the records of children who underwent air reduction for ileocolic or ileo-ileocolic intussusception over an 8-year period. We sorted data from 566 children according to whether a rectal balloon was used in the reduction, and further sorted them by type and experience level of the practitioner. Using logistic regression analyses, we identified risk factors for iatrogenic bowel perforation or failed reduction.

RESULTS

Significant associations with bowel perforation included balloon use (P=0.038), age <1 year (P<0.0001), and attending physician's level of experience <5 years (P=0.043). Younger age was associated with both perforation (P<0.0001) and procedural failure (P=0.001). The risk-adjusted predicted probability of perforation decreased with age, approaching zero by 10 months regardless of balloon use. For cases without bowel resection, the risk-adjusted predicted probability of failure decreased toward zero by 30 months with balloon use, while remaining constant at 3-12% regardless of age when not using a balloon.

CONCLUSION

The likelihood of a successful air reduction might be safely increased by using an inflated rectal balloon in children older than 9 months. Use of a balloon in younger infants is associated with a higher risk of iatrogenic bowel injury.

摘要

背景

肠套叠是幼儿肠梗阻的常见原因,主要通过空气灌肠复位治疗。关于有无直肠球囊辅助空气灌肠复位的安全性和有效性的文献较少。

目的

确定直肠球囊封堵在空气灌肠复位中的安全性和有效性。

材料与方法

我们回顾性分析了8年间因回结肠或回-回结肠型肠套叠接受空气灌肠复位治疗的儿童的病历。我们根据复位过程中是否使用直肠球囊对566名儿童的数据进行分类,并进一步按从业者的类型和经验水平进行分类。通过逻辑回归分析,我们确定了医源性肠穿孔或复位失败的危险因素。

结果

与肠穿孔显著相关的因素包括使用球囊(P=0.038)、年龄<1岁(P<0.0001)以及主治医生的经验水平<5年(P=0.043)。年龄较小与穿孔(P<0.0001)和操作失败(P=0.001)均相关。经风险调整后的穿孔预测概率随年龄增长而降低,无论是否使用球囊,到10个月时接近零。对于未行肠切除的病例,使用球囊时经风险调整后的失败预测概率在30个月时降至零,而不使用球囊时无论年龄如何,失败概率均保持在3%-12%不变。

结论

对于9个月以上的儿童,使用充气直肠球囊可安全地提高空气灌肠复位成功的可能性。在较小婴儿中使用球囊会增加医源性肠损伤的风险。

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本文引用的文献

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Pediatr Radiol. 2017 Oct;47(11):1471-1476. doi: 10.1007/s00247-017-3902-1. Epub 2017 Jun 3.
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Meta-analysis of Air Versus Liquid Enema for Intussusception Reduction in Children.空气灌肠与液体灌肠治疗儿童肠套叠复位效果的Meta分析
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Current methods for reducing intussusception: survey results.当前减少肠套叠的方法:调查结果
小儿肠套叠的治疗:一家转诊中心的 15 年经验。
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Therapeutic enema for pediatric ileocolic intussusception: using a balloon catheter improves efficacy.小儿回结肠套叠的治疗性灌肠:使用球囊导管可提高疗效。
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Risk factors for surgery in pediatric intussusception in the era of pneumatic reduction.空气灌肠复位时代小儿肠套叠手术的危险因素。
J Pediatr Surg. 2013 May;48(5):1032-6. doi: 10.1016/j.jpedsurg.2013.02.021.
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Needle decompression to avoid tension pneumoperitoneum and hemodynamic compromise after pneumatic reduction of pediatric intussusception.针式减压以避免小儿肠套叠气动复位后张力性气腹和血液动力学障碍。
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Pediatr Radiol. 2013 Jun;43(6):649-56. doi: 10.1007/s00247-012-2552-6. Epub 2012 Dec 20.
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