内镜超声在食管癌远端及腹腔干淋巴结转移诊断中的准确性：一项Meta分析与系统评价
Accuracy of endoscopic ultrasound in the diagnosis of distal and celiac axis lymph node metastasis in esophageal cancer: a meta-analysis and systematic review.
作者信息
Puli Srinivas R, Reddy Jyotsna B K, Bechtold Matthew L, Antillon Mainor R, Ibdah Jamal A
机构信息
Division of Gastroenterology and Hepatology, University of Missouri-Columbia, One Hospital Drive, Columbia, MO 65212, USA.
出版信息
Dig Dis Sci. 2008 Sep;53(9):2405-14. doi: 10.1007/s10620-007-0152-3. Epub 2007 Dec 20.
BACKGROUND
Published data on the accuracy of endoscopic ultrasound (EUS) for staging distant and celiac axis lymph node (CLN) metastasis in patients with esophageal cancer (ECA) has varied.
AIM
To evaluate the accuracy of EUS in diagnosing distal and CLN metastasis in ECA patients.
STUDY SELECTION
EUS studies confirmed by surgery were selected.
STATISTICAL METHOD
Pooling was conducted by both fixed and random-effects models.
RESULTS
Data were extracted from 25 studies (N = 2029) which met the inclusion criteria. In ECA patients, pooled sensitivity of EUS was 67.2% (95% CI: 62.6-71.6) in diagnosis of distal metastasis and 66.6% (95% CI: 61.9-71.1) in diagnosis of CLN metastasis. EUS had a pooled specificity of 97.9% (95% CI: 97.1-98.6) for distal metastasis and 98.1% (95% CI: 97.3-98.7) for CLN metastasis.
CONCLUSIONS
Although EUS has excellent specificity in accurately diagnosing distal and CLN metastasis in patients with ECA, the sensitivity is low.
背景
关于内镜超声（EUS）对食管癌（ECA）患者远处转移和腹腔干淋巴结（CLN）转移分期准确性的已发表数据各不相同。
目的
评估EUS在诊断ECA患者远处和CLN转移中的准确性。
研究选择
选择经手术证实的EUS研究。
统计方法
采用固定效应模型和随机效应模型进行汇总分析。
结果
从25项符合纳入标准的研究（N = 2029）中提取数据。在ECA患者中，EUS诊断远处转移的汇总敏感性为67.2%（95%置信区间：62.6 - 71.6），诊断CLN转移的汇总敏感性为66.6%（95%置信区间：61.9 - 71.1）。EUS诊断远处转移的汇总特异性为97.9%（95%置信区间：97.1 - 98.6），诊断CLN转移的汇总特异性为98.1%（95%置信区间：97.3 - 98.7）。
结论
尽管EUS在准确诊断ECA患者远处和CLN转移方面具有出色的特异性，但敏感性较低。
Zotero 插件