Shnitko T A, Orlov A A, Tolkunov B F
I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, 44 M. Torez Prospekt, 194223, St. Petersburg, Russia.
Neurosci Behav Physiol. 2008 Jan;38(1):81-6. doi: 10.1007/s11055-008-0011-5.
The levels of activity of monkey putamen neurons were studied during multistage behavior. Two groups of neuron activity patterns were identified. One was a pattern of low activity, less than twice the background level; the other was a pattern of high activity, exceeding the background by a greater factor. Neither type of pattern was linked with defined neurons, but both were associated with particular stages in the behavior. Low-activity patterns were recorded primarily at stages associated with the warning signal and receipt of the food reward at the stages completing the task. High-activity patterns were associated with the animal performing actions in response to the conditioned stimulus and with the decision-taking stage, when performance of the actions involved selection of the right or left hand. In addition, the number of these patterns increased significantly in relation to signals indicating correct performance of the task. Key moments in the behavior were found to be associated with increases in the numbers of high-activity patterns and simultaneous decreases in the number of low-activity patterns.
在多阶段行为过程中，对猴子壳核神经元的活动水平进行了研究。识别出了两组神经元活动模式。一组是低活动模式，低于背景水平的两倍；另一组是高活动模式，超过背景水平的幅度更大。这两种模式都与特定的神经元无关，但都与行为中的特定阶段相关。低活动模式主要记录在与警告信号相关的阶段以及在完成任务的阶段获得食物奖励时。高活动模式与动物对条件刺激做出反应的动作执行阶段以及决策阶段相关，此时动作的执行涉及选择右手或左手。此外，这些模式的数量相对于表明任务正确执行的信号显著增加。发现行为中的关键时刻与高活动模式数量的增加以及低活动模式数量的同时减少有关。
