Pinto Magali Luci, Olyntho-Tokunaga Heloisa Helena Vieira, Souccar Caden, Schoorlemmer Guus H M, Lapa Rita De Cássia Ribeiro Da Silva
Department of Histology, Universidade Federal de São Paulo, São Paulo, Brazil.
Somatosens Mot Res. 2007 Dec;24(4):221-5. doi: 10.1080/08990220701802950.
We studied projections from the interstitial system of the spinal trigeminal tract (InSy-S5T) to the red nucleus of the mouse with retrograde tracers (fluorogold and latex microbeads impregnated with rhodamine and fluorescein). Injections in the magnocellular part of the red nucleus caused labeling of cells in the rostral, intermediate, and caudal paratrigeminal nucleus (Pa5), dorsal paramarginal nucleus (PaMD), insular trigemeo-lateral cuneate nucleus (I5CuL), and the trigeminal extension of the parvocellular reticular formation (5RPC). All projections were bilateral, but contralateral projections were stronger. The number of retrogradely labeled cells in the InSy-S5T in 3-, 6-, and 12-month-old mice was similar. Injections restricted to the parvocellular red nucleus did not label the nuclei of the InSy-S5T. This projection from the InSy-S5T to the red nucleus may mediate modulation of the facial muscles by pain and other sensory information.
我们使用逆行示踪剂（荧光金以及用罗丹明和荧光素浸渍的乳胶微珠）研究了小鼠脊髓三叉神经束间质系统（InSy-S5T）至红核的投射。向红核大细胞部注射示踪剂导致三叉神经旁核嘴侧、中间和尾侧部（Pa5）、背侧旁缘核（PaMD）、岛侧三叉-外侧楔状核（I5CuL）以及小细胞网状结构的三叉神经延伸部（5RPC）的细胞被标记。所有投射均为双侧性，但对侧投射更强。3个月、6个月和12个月龄小鼠InSy-S5T中逆行标记细胞的数量相似。局限于小细胞红核的注射未标记InSy-S5T的核团。从InSy-S5T至红核的这一投射可能介导疼痛和其他感觉信息对面部肌肉的调制。
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