隐静脉搭桥移植血管的经皮介入治疗——长期疗效

Percutaneous intervention on the saphenous vein bypass grafts--long-term outcomes.

作者信息

Bansal Darpan, Muppidi Raghu, Singla Sandeep, Sukhija Rishi, Zarich Stuart, Mehta Jawahar L, Sachdeva Rajesh

机构信息

Division of Cardiovascular Medicine, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

出版信息

Catheter Cardiovasc Interv. 2008 Jan 1;71(1):58-61. doi: 10.1002/ccd.21413.

DOI:10.1002/ccd.21413

PMID:18098183

Abstract

BACKGROUND/OBJECTIVE: In this era of drug eluting stents (DES), the long-term outcome of percutaneous intervention (PCI) on saphenous venous grafts (SVG) is unknown. The objective of the study was to compare the long-term outcomes of DES versus bare metal stent (BMS) in this population and to determine the predictors of outcomes.

METHODS

We reviewed the medical records of all patients who had PCI performed during January 2003 to February 2005 to obtain data cardiac risk factors, medications at discharge, angiographic details and outcomes.

RESULTS

One hundred and nine patient had PCI to SVG; of these, 37 patients received DES and the remaining had BMS. Over a mean follow-up of 33 months, the PCI using DES was associated with 30% restenosis, 35% target vessel revascularization (TVR) and major adverse cardiac event (MACE) rate of 46% versus 35% restenosis, 38% TVR and 50% MACE rate with BMS. There was no significant difference in long-term outcome with DES as compared to BMS.

CONCLUSION

There was no difference in the long-term outcomes of PCI on SVG irrespective of the type of stent used.

摘要

背景/目的：在药物洗脱支架（DES）时代，经皮冠状动脉介入治疗（PCI）用于大隐静脉旁路移植血管（SVG）的长期疗效尚不清楚。本研究的目的是比较DES与裸金属支架（BMS）在该人群中的长期疗效，并确定疗效的预测因素。

方法

我们回顾了2003年1月至2005年2月期间所有接受PCI治疗患者的病历，以获取心脏危险因素、出院时用药、血管造影细节和疗效等数据。

结果

109例患者接受了SVG的PCI治疗；其中，37例患者接受了DES，其余患者接受了BMS。在平均33个月的随访中，使用DES的PCI患者的再狭窄率为30%，靶血管重建率（TVR）为35%，主要不良心脏事件（MACE）发生率为46%；而使用BMS的患者的再狭窄率为35%，TVR为38%，MACE发生率为50%。与BMS相比，DES的长期疗效无显著差异。