Mali Jorge Junior, Valezi Antonio Carlos, de Menezes Marco Cezar Lopes
Department of Surgery, State University of Londrina, Parana, Brazil.
Obes Surg. 2007 Oct;17(10):1287-91. doi: 10.1007/s11695-007-9230-z.
An underlying major aim of bariatric surgery is weight loss and its long-term maintainance. In spite of this, most studies regarding weight loss after surgical treatment of morbid obesity, show 3-year follow-up results. We evaluated the effectiveness of Silastic ring Roux-en-Y gastric bypass (SR-RYGBP) in promoting significant weight loss after a 5-year follow-up at the Londrina State University Hospital.
From May 1999 to December 2000, 211 morbidly obese patients were submitted to SR-RYGBP, by the same surgical team. The study's design was longitudinal, prospective and descriptive. The analysis of postoperative ponderal decrease was based on excess weight loss in percentage (%EWL) and the calculation of the BMI. Therapeutic failure was considered when patients lost <50% of excess weight at 2-years follow-up.
Patient loss to follow-up loss was 13%; therefore 183 patients were included in this study. The average global EWL was: 67.6% +/- 14.9 at the first postoperative year; 72.6% +/- 14.9 at the second year; and 69.7% +/- 15.1 in the fifth postoperative year. Surgical treatment failure occurred in 12 patients (6.5%) during the 5-year follow-up.
SR-RYGBP was effective in promoting and maintaining weight loss in the long-term, with a low failure rate.
减肥手术的一个潜在主要目标是减轻体重并长期维持。尽管如此，大多数关于病态肥胖手术治疗后体重减轻的研究都显示的是3年随访结果。我们在隆德里纳州立大学医院对硅橡胶环Roux-en-Y胃旁路术（SR-RYGBP）进行了5年随访，以评估其在促进显著体重减轻方面的有效性。
1999年5月至2000年12月，同一手术团队对211例病态肥胖患者实施了SR-RYGBP。该研究的设计为纵向、前瞻性和描述性。术后体重减轻的分析基于超重减轻百分比（%EWL）和体重指数（BMI）的计算。当患者在2年随访时超重减轻<50%时，视为治疗失败。
患者失访率为13%；因此，本研究纳入了183例患者。术后第一年的平均总体%EWL为：67.6%±14.9；第二年为72.6%±14.9；术后第五年为69.7%±15.1。在5年随访期间，12例患者（6.5%）出现手术治疗失败。
SR-RYGBP在长期促进和维持体重减轻方面有效，失败率低。
