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腹腔镜硅橡胶环迷你胃旁路术(SR-MGBP):单中心长达11年的研究结果

Laparoscopic Silastic Ring Mini-Gastric Bypass (SR-MGBP): Up to 11-Year Results from a Single Centre.

作者信息

Sheikh Laila, Pearless Lyn A, Booth Michael Wc

机构信息

Department of Surgery North Shore Hospital, 124 Shakespeare Road, Takapuna, Auckland, New Zealand.

Waitemata Specialist Centre, 13-15 Shea terrace, Takapuna, Auckland, New Zealand.

出版信息

Obes Surg. 2017 Sep;27(9):2229-2234. doi: 10.1007/s11695-017-2659-9.

Abstract

BACKGROUND

Bariatric surgery is well established as an effective method for treating obesity and its related comorbidities. The laparoscopic mini-gastric bypass (MGBP) represents a simpler alternative to a Roux-en-Y gastric bypass (RYGBP). The placement of a silastic ring (SR) may enhance excess weight loss and minimize weight regain. This study reports long-term results from a cohort of patients undergoing a SR-MGBP in a single centre.

METHODS

Long-term outcomes (up to 11 years) in a cohort of 156 patients undergoing surgery between August 2005 and January 2008 were analysed. A combination of follow-up questionnaires and electronic hospital records were used to assess weight loss, comorbidity resolution and complications.

RESULTS

A total of 156 patients (mean body mass index 46 kg/m) underwent surgery. Ninety-two patients responded to the follow-up questionnaires. Computer-based hospital information was available on a total of 139 patients. Mean percent excess weight loss (%EWL) at 11 years was 84.3%. Comorbidity resolution, determined by medication use, showed a reduction in diabetes (21.8% to 7.1%), hypertension (37.2% to 21.4%) and hypercholesterolaemia (40.4% to 13.4%). Five of 139 patients (3.6%) had SR problems needing removal. Two other patients had the SR changed to a bigger size and a further two had endoscopic removal of the SR for erosion. Of the 139 patients, 9.4% required conversion to a Roux-en-Y gastric bypass (RYGBP). The number of patients on anti-reflux medications increased from 5.1% to 44.6% at 11 years. There were two deaths unrelated to surgery.

CONCLUSIONS

SR-MGBP appears to be a safe and effective operation for the morbidly obese. It is durable, with good weight loss at up to 11 years post-surgery. The SR can easily be removed or exchanged for another size and is reasonable to consider when performing a MGBP. Concerns about bile reflux appear to be well founded, and some patients who are poorly controlled medically will require revision.

摘要

背景

减重手术已被公认为治疗肥胖及其相关合并症的有效方法。腹腔镜迷你胃旁路术(MGBP)是Roux-en-Y胃旁路术(RYGBP)的一种更简单的替代方法。放置硅橡胶环(SR)可能会增加体重减轻并减少体重反弹。本研究报告了在单一中心接受SR-MGBP手术的一组患者的长期结果。

方法

分析了2005年8月至2008年1月期间接受手术的156例患者的长期结局(长达11年)。采用随访问卷和电子医院记录相结合的方式评估体重减轻、合并症缓解情况和并发症。

结果

共有156例患者(平均体重指数46kg/m²)接受了手术。92例患者回复了随访问卷。共有139例患者可获取基于计算机的医院信息。术后11年时平均超重减轻百分比(%EWL)为84.3%。根据药物使用情况确定的合并症缓解情况显示,糖尿病(从21.8%降至7.1%)、高血压(从37.2%降至21.4%)和高胆固醇血症(从40.4%降至13.4%)均有所减轻。139例患者中有5例(3.6%)出现需要取出SR的问题。另外2例患者将SR更换为更大尺寸,还有2例因SR侵蚀接受了内镜下取出。在139例患者中,9.4%需要转为Roux-en-Y胃旁路术(RYGBP)。服用抗反流药物的患者数量在术后11年时从5.1%增加到44.6%。有2例死亡与手术无关。

结论

SR-MGBP似乎是一种治疗病态肥胖患者的安全有效的手术。它具有持久性,术后长达11年时减重效果良好。SR可以轻松取出或更换为其他尺寸,在进行MGBP时值得考虑。对胆汁反流的担忧似乎有充分依据,一些药物治疗效果不佳的患者需要进行翻修手术。

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