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[丁酸钠对无菌性炎症的动态调节作用]

[The dynamic modification of aseptic inflammation with sodium oxybutyrate].

作者信息

Vasil'eva L S, Kuz'menko V V, Malyshev V V

出版信息

Biull Eksp Biol Med. 1991 Nov;112(11):467-9.

PMID:1810478
Abstract

The oxybuturate sodium influence on the vessel and cells dynamics in the source of aseptic inflammation was studied. It was shown that oxybuturate sodium injection (100 mg/kg) before 30 min and after 2 and 4 hours of inflammation onset leads to suppression of microvessel reaction, reduction of macrophagic infiltrate density, decrease of macrophagic phase duration and the earliest perfection of inflammation in the whole.

摘要

研究了氧丁酸钠对无菌性炎症病灶中血管和细胞动力学的影响。结果表明,在炎症发作前30分钟以及发作后2小时和4小时注射氧丁酸钠(100毫克/千克)可导致微血管反应受到抑制、巨噬细胞浸润密度降低、巨噬细胞期持续时间缩短,总体上炎症最早得到改善。

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