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生物统计学分析在颅下颌及口面部疼痛疾病中的意义与应用。

The implications and applications of biostatistical analysis in craniomandibular and orofacial pain disorders.

作者信息

Austin D, Attanasio R

机构信息

Department of Adult Restorative Dentistry, University of Nebraska Medical Center College of Dentistry, Lincoln.

出版信息

Cranio. 1991 Jul;9(3):280-5. doi: 10.1080/08869634.1991.11678374.

DOI:10.1080/08869634.1991.11678374
PMID:1810672
Abstract

This article will acquaint the reader with the most commonly used summary statistics and their appropriate use in craniomandibular and orofacial pain disorders. Hopefully it will also encourage the reader to critically examine published papers, experimental design, and statistical treatment of data by asking these questions: Have experiments been properly designed? Has enough information been presented so that research can be repeated? Were subjects randomly assigned and treated? Was the statistical analysis described clearly and succinctly, and was it appropriate? Did the experimental data and results support the conclusions of the article? Were the findings statistically significant, and if so, were they clinically significant and meaningful? Anecdotal clinical studies of temporomandibular disorder sufferers can no longer be considered as the gold standard.

摘要

本文将使读者了解最常用的汇总统计数据及其在颅下颌和口面部疼痛疾病中的恰当应用。希望这也能促使读者通过提出以下问题来批判性地审视已发表的论文、实验设计和数据的统计处理:实验设计是否合理?是否提供了足够的信息以便重复研究?受试者是否被随机分配和治疗?统计分析是否清晰简洁地描述,且是否恰当?实验数据和结果是否支持文章的结论?研究结果在统计学上是否显著,如果是,它们在临床上是否显著且有意义?颞下颌关节紊乱症患者的轶事性临床研究再也不能被视为金标准了。

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