HARDING W B F
Calif Med. 1949 Feb;70(2):108-13.
In individuals with primary cutaneous epithelioma there may be a widespread predisposition of the basal cell layer of the epidermis toward the production of growths of this type. The differential diagnosis usually can be made on clinical characteristics, but in some instances differentiation is difficult and a correct diagnosis may be reached only by microscopic examination of the tissue. The radioresistance of this type of epithelioma is emphasized and the selection of the proper method of treatment is discussed. Consideration of the factors of (1) size and location of the lesion, (2) age, and (3) general condition of the patient may result in a decision that, in some cases, no treatment is indicated. Biochemical, cytological and pathological studies of basal cell epithelioma might lead to a clearer understanding of the nature of epitheliomas in general.
在原发性皮肤上皮瘤患者中，表皮基底细胞层可能普遍易于产生此类肿瘤。鉴别诊断通常可依据临床特征做出，但在某些情况下，鉴别存在困难，只有通过对组织进行显微镜检查才能得出正确诊断。文中强调了此类上皮瘤的放射抗性，并讨论了合适治疗方法的选择。考虑（1）病变的大小和位置、（2）年龄以及（3）患者的一般状况等因素，在某些情况下可能会得出无需治疗的决定。对基底细胞上皮瘤进行生化、细胞学和病理学研究，可能会使人们对一般上皮瘤的性质有更清晰的认识。
