Suárez I, Bodega G, Rubio M, Fernandez B
Departamento de Biología Celular y Genética, Universidad de Alcalá, Alcalá de Henares, Madrid, Spain.
J Anat. 1991 Oct;178:79-82.
The supraoptic nuclei (SON) of the hypothalamus of male and female hamsters were examined immunohistochemically at 1 month of age for possible sex differences in astroglial organisation. The morphometric analysis revealed the presence of more glial fibrillary acidic protein (GFAP) immunostaining in the SON of males as compared with females. GFAP-positive processes were located among the neurosecretory neurons in the males, but were quite scarce among these neurons in the female SON. These results indicate the existence of sexual dimorphism in the SON which could be mediated by sex steroids.
对1月龄雄性和雌性仓鼠下丘脑的视上核(SON)进行免疫组织化学检查,以探究星形胶质组织中可能存在的性别差异。形态计量分析显示,与雌性相比,雄性视上核中胶质纤维酸性蛋白(GFAP)的免疫染色更多。GFAP阳性突起位于雄性神经分泌神经元之间,但在雌性视上核的这些神经元中相当稀少。这些结果表明视上核存在性别二态性,可能由性类固醇介导。