• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

人血清中总纤溶酶和胰蛋白酶抑制剂的定量研究；链球菌疾病中总纤溶酶和胰蛋白酶抑制剂血浓度的变化，特别提及风湿热。

Quantitative studies on the total plasmin and the trypsin inhibitor of human blood serum; variations in the blood concentration of total plasmin and of trypsin inhibitor in streptococcal diseases with special reference to rheumatic fever.

作者信息

TODD E W

出版信息

J Exp Med. 1949 Mar;89(3):309-24. doi: 10.1084/jem.89.3.309.

DOI:10.1084/jem.89.3.309
PMID:18110885
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2135869/
Abstract

THE TOTAL PLASMIN AND THE TRYPSIN INHIBITOR WERE TITRATED SEPARATELY IN SAMPLES OF SERUM TAKEN AT WEEKLY INTERVALS FROM THREE DIFFERENT GROUPS OF SCARLET FEVER PATIENTS

(a) those who did not develop any complications, (b) those who developed purulent complications, and (c) those who developed rheumatic fever. When these determinations were plotted, it was found that the resulting curves showed characteristic patterns for each of the diseases investigated. The uncomplicated cases had plasmin curves which were considerably higher on the charts than the inhibitor curves. The septic cases had plasmin and inhibitor curves which were closer together on the charts. The rheumatic cases had plasmin and inhibitor curves which were close together and which crossed at the time of rheumatic activity so that the inhibitor curve reached a higher level than the plasmin curve.

摘要

对三组不同的猩红热患者每周采集的血清样本分别进行总纤溶酶和胰蛋白酶抑制剂的滴定

（a）未出现任何并发症的患者；（b）出现化脓性并发症的患者；（c）出现风湿热的患者。将这些测定结果绘制成图时，发现所得曲线显示了所研究的每种疾病的特征模式。无并发症的病例，其纤溶酶曲线在图表上比抑制剂曲线高得多。败血症病例的纤溶酶和抑制剂曲线在图表上靠得更近。风湿热病例的纤溶酶和抑制剂曲线靠得很近，且在风湿活动时相交，使得抑制剂曲线达到比纤溶酶曲线更高的水平。

相似文献

1
Quantitative studies on the total plasmin and the trypsin inhibitor of human blood serum; variations in the blood concentration of total plasmin and of trypsin inhibitor in streptococcal diseases with special reference to rheumatic fever.人血清中总纤溶酶和胰蛋白酶抑制剂的定量研究；链球菌疾病中总纤溶酶和胰蛋白酶抑制剂血浓度的变化，特别提及风湿热。
J Exp Med. 1949 Mar;89(3):309-24. doi: 10.1084/jem.89.3.309.
2
Quantitative studies on the total plasmin and the trypsin inhibitor of human blood serum; methods for the titration of total plasmin and of trypsin inhibitor.人血清中总纤溶酶和胰蛋白酶抑制剂的定量研究；总纤溶酶和胰蛋白酶抑制剂的滴定方法。
J Exp Med. 1949 Mar;89(3):295-308. doi: 10.1084/jem.89.3.295.
3
Serum inhibitors of elastase, trypsin, and plasmin in chronic rheumatic diseases.慢性风湿性疾病中弹性蛋白酶、胰蛋白酶和纤溶酶的血清抑制剂
Ann Rheum Dis. 1966 Sep;25(5):450-5. doi: 10.1136/ard.25.5.450.
4
[Acid-stable inhibitor of trypsin, plasmin and kallikrein from rabbit blood serum].[来自兔血清的对胰蛋白酶、纤溶酶和激肽释放酶的酸稳定抑制剂]
Vopr Med Khim. 1966 May-Jun;12(3):325-7.
5
Observations on the inhibition of preparations of porcine plasmin by serum and by urinary trypsin inhibitor (mingin).关于血清和尿胰蛋白酶抑制剂（明胶酶）对猪纤溶酶制剂抑制作用的观察
Scand J Clin Lab Invest. 1965;17(5):410-2.
6
Studies on the inhibition of proteolytic enzymes by serum. I. The mechanism of the inhibition of trypsin, plasmin, and chymotrypsin by serum using fibrin tagged with I131 as a substrate.血清对蛋白水解酶的抑制作用研究。I. 以I131标记的纤维蛋白为底物研究血清对胰蛋白酶、纤溶酶和糜蛋白酶的抑制机制。
J Exp Med. 1952 Jun;95(6):571-91. doi: 10.1084/jem.95.6.571.
7
The plasmin inhibitor of human plasma. IV. Its action on plasmin, trypsin, chymotrypsin, and thrombin.人血浆中的纤溶酶抑制剂。IV. 其对纤溶酶、胰蛋白酶、糜蛋白酶和凝血酶的作用。
J Biol Chem. 1966 Nov 10;241(21):5102-7.
8
Purification and reaction mechanisms of the primary inhibitor of plasmin from human plasma.人血浆纤溶酶原激活物抑制物-1的纯化及反应机制
Biochem J. 1978 Nov 1;175(2):635-41. doi: 10.1042/bj1750635.
9
[About degradation products of the inter-alpha-trypsin inhibitor in serum. I. The inter-alpha-trypsin inhibitor as precursor of the acid stable trypsin-plasmin-inhibitor of the serum (author's transl)].[关于血清中α-胰蛋白酶抑制剂的降解产物。I. α-胰蛋白酶抑制剂作为血清中酸稳定的胰蛋白酶-纤溶酶抑制剂的前体（作者译）]
Klin Wochenschr. 1977 Apr 1;55(7):337-42. doi: 10.1007/BF01488112.
10
C1 inactivator inhibition by plasmin.纤溶酶对C1灭活剂的抑制作用。
J Clin Invest. 1970 Mar;49(3):568-75. doi: 10.1172/JCI106267.

本文引用的文献

1
Quantitative studies on the total plasmin and the trypsin inhibitor of human blood serum; methods for the titration of total plasmin and of trypsin inhibitor.人血清中总纤溶酶和胰蛋白酶抑制剂的定量研究；总纤溶酶和胰蛋白酶抑制剂的滴定方法。
J Exp Med. 1949 Mar;89(3):295-308. doi: 10.1084/jem.89.3.295.