GOGGIO A F
Calif Med. 1949 Mar;70(3):167-70.
A number of recent reports in the literature have told of cure of psittacosis in man following enormous doses of penicillin in the early stages of the disease. In most of these cases, however, the infection was experimentally induced in laboratory studies. Given late and in inadequate amounts, penicillin apparently has no beneficial effect. With a means of treatment at hand, and effective if started early, careful analysis of all cases of "atypical pneumonia" is indicated with a view to determining if the infecting agent might not be the psittacosis virus. A history of contact with birds or bird droppings should be sought in all cases of "atypical pneumonia."A case is reported in which the patient, because of contact with birds, was suspected early of having psittacosis. No benefit was noted following therapy with 100,000 units of penicillin every three hours for one day, but rapid recovery ensued when the dose was doubled.
文献中最近有一些报道称,在鹦鹉热疾病早期给予大剂量青霉素后,人类患者得以治愈。然而,在大多数此类病例中,感染是在实验室研究中通过实验诱导产生的。如果用药过晚且剂量不足,青霉素显然没有有益效果。鉴于有了一种手头可用且早期使用有效的治疗方法,应对所有“非典型肺炎”病例进行仔细分析,以确定感染源是否可能是鹦鹉热病毒。在所有“非典型肺炎”病例中,都应询问患者是否有与鸟类或鸟粪接触的病史。本文报告了一例病例,该患者因接触鸟类,早期被怀疑患有鹦鹉热。每三小时注射100,000单位青霉素,治疗一天后未见疗效,但当剂量加倍后,患者迅速康复。